Rabbit anti-Human ATAD2 Polyclonal Antibody | anti-ATAD2 antibody

ATAD2 Rabbit Polyclonal

Cat. Num. AAA766887

• Gene Names: ATAD2; ANCCA; CT137; PRO2000
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ATAD2; Polyclonal Antibody; ATAD2 Rabbit Polyclonal; anti-ATAD2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1390

• Applicable Applications for anti-ATAD2 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: ATPase family, AAA domain containing 2
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS766887 (ATAD2 Antibody) at dilution of 1:600)

NCBI and Uniprot Product Information

• NCBI GI #: 24497618
• NCBI GeneID: 29028
• NCBI Accession #: NP_054828.2
• NCBI GenBank Nucleotide #: NM_014109.3
• Molecular Weight: 47,986 Da
• NCBI Official Full Name: ATPase family AAA domain-containing protein 2
• NCBI Official Synonym Full Names: ATPase family, AAA domain containing 2
• NCBI Official Symbol: ATAD2
• NCBI Official Synonym Symbols: ANCCA; CT137; PRO2000
• NCBI Protein Information: ATPase family AAA domain-containing protein 2
• UniProt Protein Name: ATPase family AAA domain-containing protein 2
• Protein Family: ATPase family AAA domain-containing protein
• UniProt Gene Name: ATAD2
• UniProt Synonym Gene Names: ANCCA
• UniProt Entry Name: ATAD2_HUMAN

NCBI Description

A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain. [provided by RefSeq, Jul 2008]

Uniprot Description

ATAD2: a member of the AAA ATPase family. Contains a bromodomain, a domain known to interact specifically with acetylated lysine. Two alternatively spliced isoforms of the human protein have been reported.

Protein type: EC 3.6.1.3; Hydrolase; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 8q24.13

Cellular Component: nucleoplasm; nucleus

Molecular Function: ATP binding; ATPase activity; chromatin binding; histone binding

Biological Process: chromatin modification; negative regulation of chromatin silencing; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent