Western Blot (WB)
(Western blot analysis of ARIDB3 Antibody (C-term) in K562 cell line lysates (35ug/lane). ARIDB3 (arrow) was detected using the purified Pab.)
Rabbit anti-Human AT-rich Interactive Domain-containing Protein 3B Polyclonal Antibody | anti-ARID3B antibody
AT-rich Interactive Domain-containing Protein 3B, CT (ARID3B, ARID Domain-containing Protein 3B, Bright-like Protein, Bright and Dead Ringer Protein, BDP, DRIL2) (PE)
FLISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of ARIDB3 Antibody (C-term) in K562 cell line lysates (35ug/lane). ARIDB3 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of ARIDB3 Antibody (C-term) in K562 cell line lysates (35ug/lane). ARIDB3 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human testis tissue reacted with ARIDB3 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human testis tissue reacted with ARIDB3 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]
Uniprot Description
ARID3B: Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor
Chromosomal Location of Human Ortholog: 15q24
Cellular Component: nucleoplasm; nucleus
Molecular Function: DNA binding
Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
Research Articles on ARID3B
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Product Notes
The ARID3B arid3b (Catalog #AAA6464330) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AT-rich Interactive Domain-containing Protein 3B, CT (ARID3B, ARID Domain-containing Protein 3B, Bright-like Protein, Bright and Dead Ringer Protein, BDP, DRIL2) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AT-rich Interactive Domain-containing Protein 3B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-1:50 FLISA: 1:1,000 WB: 1:50-1:100 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ARID3B arid3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AT-rich Interactive Domain-containing Protein 3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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