Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ASB8 Polyclonal Antibody at dilution 1:50)
Rabbit ASB8 Polyclonal Antibody | anti-ASB8 antibody
ASB8 Polyclonal Antibody
Gene Names
ASB8; PP14212
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ASB8; Polyclonal Antibody; ASB8 Polyclonal Antibody; PP14212; anti-ASB8 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
3mg/mL (varies by lot)
Sequence Length
288
Applicable Applications for anti-ASB8 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:25-1:100
Immunogen
Recombinant protein of human ASB8
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ASB8 Polyclonal Antibody at dilution 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ASB8 Polyclonal Antibody at dilution 1:50)
Related Product Information for anti-ASB8 antibody
ASB-8 (ankyrin repeat and SOCS box-containing 8) is a 288 amino acid member of the ASB family that contains one SOCS box domain and four ANK repeats. Localized to the cytoplasm, ASB-8 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. The highest level of ASB-8 expression has been detected in skeletal muscle. ASB-8 is also expressed in heart, brain, placenta, liver, kidney and pancreas.
Product Categories/Family for anti-ASB8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
31,642 Da
NCBI Official Full Name
ASB8
NCBI Official Synonym Full Names
ankyrin repeat and SOCS box containing 8
NCBI Official Symbol
ASB8
NCBI Official Synonym Symbols
PP14212
NCBI Protein Information
ankyrin repeat and SOCS box protein 8; ASB-8; ankyrin repeat and SOCS box-containing 8
UniProt Protein Name
Ankyrin repeat and SOCS box protein 8
Protein Family
UniProt Gene Name
ASB8
UniProt Synonym Gene Names
ASB-8
UniProt Entry Name
ASB8_HUMAN
Uniprot Description
ASB8: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Chromosomal Location of Human Ortholog: 12q13.11
Cellular Component: cytoplasm
Biological Process: protein ubiquitination
Research Articles on ASB8
Similar Products
Product Notes
The ASB8 asb8 (Catalog #AAA2529356) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ASB8 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ASB8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the ASB8 asb8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ASB8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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