Rabbit anti-Human ART3 Polyclonal Antibody | anti-ART3 antibody

ART3, CT (Ecto-ADP-ribosyltransferase 3, NAD(P)(+)-arginine ADP-ribosyltransferase 3, Mono(ADP-ribosyl) Transferase 3, TMART) (AP)

Cat. Num. AAA6464132

• Gene Names: ART3; ARTC3
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein G Affinity Chromatography.
• Synonyms: ART3; Polyclonal Antibody; CT (Ecto-ADP-ribosyltransferase 3; NAD(P)(+)-arginine ADP-ribosyltransferase 3; Mono(ADP-ribosyl) Transferase 3; TMART) (AP); anti-ART3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ART3.
• Purity/Purification: Purified by Protein G Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-ART3 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-1:500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from the C-terminal region of human ART3 (KLH).
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: May be stored at 4 degree C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of ART3 Antibody (C-term) in HL60 cell line lysates (25ug/lane). ART3(arrow) was detected using the purified Pab (4 ug/ml).)

Product Categories/Family for anti-ART3 antibody

Antibodies; Enzymes; Ribosyltransferase

References

1. Strausberg, R.L., et al., Proc. Natl. Acad. Sci. USA 99(26):16899-16903 (2002). 2. Koch-Nolte, F., et al., Genomics 39(3):370-376 (1997). 3. Levy, I., et al., FEBS Lett. 382(3):276-280 (1996).

NCBI and Uniprot Product Information

• NCBI GI #: 21361167
• NCBI GeneID: 419
• NCBI Accession #: NP_001170
• NCBI GenBank Nucleotide #: NM_001179
• UniProt Accession #: Q13508
• Molecular Weight: 40kDa
• NCBI Official Full Name: ecto-ADP-ribosyltransferase 3 isoform b
• NCBI Official Synonym Full Names: ADP-ribosyltransferase 3
• NCBI Official Symbol: ART3
• NCBI Official Synonym Symbols: ARTC3
• NCBI Protein Information: ecto-ADP-ribosyltransferase 3
• UniProt Protein Name: Ecto-ADP-ribosyltransferase 3
• Protein Family: Ecto-ADP-ribosyltransferase
• UniProt Gene Name: ART3
• UniProt Synonym Gene Names: TMART; ARTC3
• UniProt Entry Name: NAR3_HUMAN

NCBI Description

This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

ART3: an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Protein type: Membrane protein, integral; Membrane protein, GPI anchor; EC 2.4.2.31; Transferase

Chromosomal Location of Human Ortholog: 4q21.1|4p15.1-p14

Cellular Component: integral to plasma membrane

Molecular Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity

Biological Process: protein amino acid ADP-ribosylation