Rabbit ARL2BP Polyclonal Antibody | anti-ARL2BP antibody

ARL2BP Antibody

Cat. Num. AAA7131145

• Gene Names: ARL2BP; BART; BART1
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: ARL2BP; Polyclonal Antibody; ARL2BP Antibody; ADP-ribosylation factor-like 2 binding; AR2BP; Arf-like 2 binding protein BART1; BART1; anti-ARL2BP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.

• Applicable Applications for anti-ARL2BP antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500-1:3000
• Immunogen: Synthesized peptide derived from internal of human ARL2BP.
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blot analysis of extracts from A549 cells, using ARL2BP antibody. )

Product Categories/Family for anti-ARL2BP antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 6912268
• NCBI GeneID: 23568
• NCBI Accession #: NP_036238.1
• NCBI GenBank Nucleotide #: NM_012106.3
• UniProt Accession #: Q9Y2Y0; Q504R0; B3KQJ5
• Molecular Weight: 18,822 Da
• NCBI Official Full Name: ADP-ribosylation factor-like protein 2-binding protein
• NCBI Official Synonym Full Names: ADP-ribosylation factor-like 2 binding protein
• NCBI Official Symbol: ARL2BP
• NCBI Official Synonym Symbols: BART; BART1
• NCBI Protein Information: ADP-ribosylation factor-like protein 2-binding protein; binder of Arl2; binder of Arl Two; binder of ARF2 protein 1; ARF-like 2-binding protein; Arf-like 2 binding protein BART1
• UniProt Protein Name: ADP-ribosylation factor-like protein 2-binding protein
• Protein Family: ADP-ribosylation factor-like protein 2-binding protein
• UniProt Gene Name: ARL2BP
• UniProt Synonym Gene Names: BART; BART1; ARF-like 2-binding protein
• UniProt Entry Name: AR2BP_HUMAN

NCBI Description

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]

Uniprot Description

ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.; Mitochondrial

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: centrosome; mitochondrial intermembrane space; spindle; midbody; nucleus; cilium

Molecular Function: protein binding; transcription coactivator activity

Biological Process: regulation of catalytic activity; maintenance of protein localization in nucleus; signal transduction; positive regulation of tyrosine phosphorylation of Stat3 protein

Disease: Retinitis Pigmentosa With Or Without Situs Inversus