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Immunohistochemistry (IHC) (Anti-ARHGEF17 / TEM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit anti-Human ARHGEF17 / TEM4 Polyclonal Antibody | anti-ARHGEF17 antibody

Rabbit Polyclonal to Human ARHGEF17 / TEM4

Gene Names
ARHGEF17; TEM4; P164RHOGEF; p164-RhoGEF
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
ARHGEF17 / TEM4; Polyclonal Antibody; Rabbit Polyclonal to Human ARHGEF17 / TEM4; Anti-ARHGEF17 / TEM4 Antibody (Internal) IHC-plus; ARHGEF17; KIAA0337; TEM4; Tumor endothelial marker 4; p164-RhoGEF; p164RHOGEF; Human ARHGEF17; anti-ARHGEF17 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
2063
Applicable Applications for anti-ARHGEF17 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
18 amino acid peptide near the center of human TEM4.
Immunogen
ARHGEF17 / TEM4 antibody was raised against 18 amino acid peptide near the center of human TEM4.
Antigen Modification
Internal
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-ARHGEF17 / TEM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-ARHGEF17 / TEM4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-ARHGEF17 / TEM4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-ARHGEF17 / TEM4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-ARHGEF17 / TEM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-ARHGEF17 / TEM4 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western blot of TEM4 in Jurkat Cell lysate with TEM4 antibody at (A) 1 and (B) 2 ug/ml. Below: Immunohistochemistry of TEM4 in human spleen tissue with TEM4 antibody at 2.5 ug/ml.)

Western Blot (WB) (Western blot of TEM4 in Jurkat Cell lysate with TEM4 antibody at (A) 1 and (B) 2 ug/ml. Below: Immunohistochemistry of TEM4 in human spleen tissue with TEM4 antibody at 2.5 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
221,673 Da
NCBI Official Full Name
rho guanine nucleotide exchange factor 17
NCBI Official Synonym Full Names
Rho guanine nucleotide exchange factor (GEF) 17
NCBI Official Symbol
ARHGEF17
NCBI Official Synonym Symbols
TEM4; P164RHOGEF; p164-RhoGEF
NCBI Protein Information
rho guanine nucleotide exchange factor 17; tumor endothelial marker 4; 164 kDa Rho-specific guanine-nucleotide exchange factor; Rho-specific guanine-nucleotide exchange factor 164 kDa
UniProt Protein Name
Rho guanine nucleotide exchange factor 17
UniProt Gene Name
ARHGEF17
UniProt Synonym Gene Names
KIAA0337; TEM4; p164-RhoGEF; p164RhoGEF
UniProt Entry Name
ARHGH_HUMAN

Uniprot Description

ARHGEF17: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.

Protein type: GEFs; GEFs, Rac/Rho

Chromosomal Location of Human Ortholog: 11q13.4

Cellular Component: cytosol

Molecular Function: Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity

Biological Process: regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction; actin cytoskeleton organization and biogenesis; positive regulation of GTPase activity

Research Articles on ARHGEF17

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Product Notes

The ARHGEF17 arhgef17 (Catalog #AAA242381) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ARHGEF17 / TEM4 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGEF17 / TEM4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the ARHGEF17 arhgef17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGEF17 / TEM4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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