Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human ARHGAP17/NADRIN Polyclonal Antibody | anti-ARHGAP17/NADRIN antibody
Anti-ARHGAP17/NADRIN Antibody (aa41-70)
IHC-P: 1:100
WB: 1:1000
For long term storage store at -20 degree C.
Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(ARHGAP17 Antibody western blot of K562 cell line lysates (35 ug/lane). The ARHGAP17 antibody detected the ARHGAP17 protein (arrow).)
Western Blot (WB)
(ARHGAP17 Antibody western blot of K562 cell line lysates (35 ug/lane). The ARHGAP17 antibody detected the ARHGAP17 protein (arrow).)
Flow Cytometry (FC/FACS)
(ARHGAP17 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(ARHGAP17 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA (MIM 165390), RAC1 (MIM 602048), and CDC42 (MIM 116952).[supplied by OMIM, Apr 2004]
Uniprot Description
Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
Research Articles on ARHGAP17/NADRIN
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Product Notes
The ARHGAP17/NADRIN arhgap17 (Catalog #AAA2401821) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ARHGAP17/NADRIN Antibody (aa41-70) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGAP17/NADRIN can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). FC/FACS: 1:10-1:50 IHC-P: 1:100 WB: 1:1000. Researchers should empirically determine the suitability of the ARHGAP17/NADRIN arhgap17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGAP17/NADRIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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