Western Blot (WB)
(Host: RabbitTarget Name: ARHGAP11ASample Type: Fetal Lung lysatesAntibody Dilution: 1.0ug/ml)
Rabbit ARHGAP11A Polyclonal Antibody | anti-ARHGAP11A antibody
ARHGAP11A Antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: ARHGAP11ASample Type: Fetal Lung lysatesAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: ARHGAP11ASample Type: Fetal Lung lysatesAntibody Dilution: 1.0ug/ml)
Target Description: The function of this protein remains unknown.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019]
Uniprot Description
ARHGAP11A: 2 isoforms of the human protein are produced by alternative splicing
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 15q13.2
Cellular Component: cytosol
Molecular Function: GTPase activator activity
Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity
Research Articles on ARHGAP11A
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Product Notes
The ARHGAP11A arhgap11a (Catalog #AAA3217674) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARHGAP11A Antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGAP11A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ARHGAP11A arhgap11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: MLGIDGLCAT PSLEGFEEGE YETPGEYKRK RRQSVGDFVS GALNKFKPNR. It is sometimes possible for the material contained within the vial of "ARHGAP11A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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