Western Blot (WB)
(ARHGAP10 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ARHGAP10 antibody detected the ARHGAP10 protein (arrow).)
Rabbit ARHGAP10 Polyclonal Antibody | anti-ARHGAP10 antibody
ARHGAP10 Antibody (Center)
Western Blot (WB)
(ARHGAP10 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ARHGAP10 antibody detected the ARHGAP10 protein (arrow).)
Western Blot (WB)
(ARHGAP10 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the ARHGAP10 antibody detected the ARHGAP10 protein (arrow).)
Immunohistochemistry (IHC)
(ARHGAP10 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ARHGAP10 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(ARHGAP10 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ARHGAP10 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(ARHGAP10 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(ARHGAP10 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Azzato, E.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(4):1140-1143(2010)
Lind, P.A., et al. Twin Res Hum Genet 13(1):10-29(2010)
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
NCBI and Uniprot Product Information
Uniprot Description
ARHGAP10: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
Protein type: Motility/polarity/chemotaxis; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 4q31.23
Cellular Component: perinuclear region of cytoplasm; plasma membrane; cytosol
Molecular Function: protein binding
Biological Process: regulation of apoptosis; regulation of small GTPase mediated signal transduction; apoptosis; small GTPase mediated signal transduction; cytoskeleton organization and biogenesis; negative regulation of apoptosis
Research Articles on ARHGAP10
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Product Notes
The ARHGAP10 arhgap10 (Catalog #AAA9203762) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 237-263. The ARHGAP10 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGAP10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the ARHGAP10 arhgap10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGAP10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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