Western Blot (WB)
((0. 01ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat Arginase, type 1/ARG1 Polyclonal Antibody | anti-ARG1 antibody
Goat anti-Arginase, type 1/ARG1 Antibody
Western Blot: Approx 37kDa band observed in Human Liver lysates (calculated MW of 34.7kDa according to NP_000036.2. Recommended concentration: 0.01-0.03ug/ml. An anonymous customer found positive results in WB on Mouse leukaemic monocyte macrophage cells (RAW 264.7).
Western Blot (WB)
((0. 01ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0. 01ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Uniprot Description
ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.5.3.1; Hydrolase; Amino Acid Metabolism - arginine and proline
Chromosomal Location of Human Ortholog: 6q23
Cellular Component: cell soma; cytoplasm; cytosol; extracellular space; mitochondrial outer membrane; neuron projection; nucleus
Molecular Function: arginase activity; manganese ion binding
Biological Process: aging; arginine catabolic process; arginine catabolic process to ornithine; collagen biosynthetic process; liver development; lung development; mammary gland involution; maternal process involved in pregnancy; positive regulation of endothelial cell proliferation; response to amine stimulus; response to amino acid stimulus; response to axon injury; response to cadmium ion; response to drug; response to herbicide; response to manganese ion; response to methylmercury; response to selenium ion; response to vitamin A; response to vitamin E; response to zinc ion; urea cycle
Disease: Argininemia
Research Articles on ARG1
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Product Notes
The ARG1 arg1 (Catalog #AAA421120) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Arginase, type 1/ARG1 Antibody reacts with Tested: Human, Mouse; Expected from sequence similarity: Human, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's Arginase, type 1/ARG1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Approx 37kDa band observed in Human Liver lysates (calculated MW of 34.7kDa according to NP_000036.2. Recommended concentration: 0.01-0.03ug/ml. An anonymous customer found positive results in WB on Mouse leukaemic monocyte macrophage cells (RAW 264.7). Researchers should empirically determine the suitability of the ARG1 arg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: REGNHKPIDY LNPPK. It is sometimes possible for the material contained within the vial of "Arginase, type 1/ARG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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