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Immunohistochemistry (IHC) (Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit AQP4/Aquaporin 4 Polyclonal Antibody | anti-AQP4 antibody

Anti-AQP4/Aquaporin 4 Antibody

Gene Names
AQP4; MIWC; WCH4
Reactivity
Human
Predicted: Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
AQP4/Aquaporin 4; Polyclonal Antibody; Anti-AQP4/Aquaporin 4 Antibody; Rabbit Polyclonal (IgG) to Rat AQP4/Aquaporin 4; AQP4; Aquaporin type4; Aquaporin 4; Aquaporin-4; HMIWC2; MIWC; WCH4; AQP-4; anti-AQP4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Human AQP4/Aquaporin 4
Purity/Purification
Affinity Purified
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Sequence Length
323
Applicable Applications for anti-AQP4 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100
WB: 1:500-1:1000
Immunogen
A synthetic peptide of human AQP4.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB)

(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB) (Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of extracts of SKOV-3 cells.)

Western Blot (WB) (Western blot analysis of extracts of SKOV-3 cells.)

Western Blot (WB)

(Western blot analysis of extracts of SKOV-3 cell line, using AQP4 antibody.)

Western Blot (WB) (Western blot analysis of extracts of SKOV-3 cell line, using AQP4 antibody.)
Related Product Information for anti-AQP4 antibody
AQP4, also known as Mercurial-insensitive water channel (MIWC), is the fourth member of the aquaporin water channel family. This osmoreceptor regulates body water balance and mediates water flow within the central nervous system. It appears to play some specific role in the functioning of skeletal muscles, retina, and auditory system. Contrary to other aquaporin family members, AQP4 is not inhibited by mercurial compounds.
Product Categories/Family for anti-AQP4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
361
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
32,300 Da
NCBI Official Full Name
aquaporin-4 isoform M1
NCBI Official Synonym Full Names
aquaporin 4
NCBI Official Symbol
AQP4
NCBI Official Synonym Symbols
MIWC; WCH4
NCBI Protein Information
aquaporin-4
UniProt Protein Name
Aquaporin-4
Protein Family
UniProt Gene Name
AQP4
UniProt Synonym Gene Names
AQP-4; MIWC

NCBI Description

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Uniprot Description

Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.

Research Articles on AQP4

Similar Products

Product Notes

The AQP4 aqp4 (Catalog #AAA2401518) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-AQP4/Aquaporin 4 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AQP4/Aquaporin 4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the AQP4 aqp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AQP4/Aquaporin 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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