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Immunohistochemistry (IHC) (Human Breast (formalin-fixed, paraffin-embedded) stained with TNFSF13 antibody at 5ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Rabbit anti-Human APRIL Polyclonal Antibody | anti-ANP32B antibody

APRIL, ID (Tumor Necrosis Factor Ligand Superfamily Member 13, A Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1, TNF-related Death Ligand 1, TNFSF13, CD256, TALL2, ZTNF2, UNQ383/PRO715)

Gene Names
ANP32B; APRIL; SSP29; PHAPI2
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by Protein G affinity chromatography.
Synonyms
APRIL; Polyclonal Antibody; ID (Tumor Necrosis Factor Ligand Superfamily Member 13; A Proliferation Inducing Ligand; TALL-2; TNF and ApoL-related Leukocyte-expressed Ligand 2; TRDL-1; TNF-related Death Ligand 1; TNFSF13; CD256; TALL2; ZTNF2; UNQ383/PRO715); Anti -APRIL; anti-ANP32B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human APRIL.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.1mg/ml BSA.
Applicable Applications for anti-ANP32B antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 2-4ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Immunogen
Synthetic peptide corresponding to aa1-17 of human APRIL (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Breast (formalin-fixed, paraffin-embedded) stained with TNFSF13 antibody at 5ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Immunohistochemistry (IHC) (Human Breast (formalin-fixed, paraffin-embedded) stained with TNFSF13 antibody at 5ug/ml followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)
Related Product Information for anti-ANP32B antibody
TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM.
Product Categories/Family for anti-ANP32B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,788 Da
NCBI Official Full Name
acidic leucine-rich nuclear phosphoprotein 32 family member B
NCBI Official Synonym Full Names
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
NCBI Official Symbol
ANP32B
NCBI Official Synonym Symbols
APRIL; SSP29; PHAPI2
NCBI Protein Information
acidic leucine-rich nuclear phosphoprotein 32 family member B; silver-stainable protein SSP29; acidic protein rich in leucines; putative HLA-DR-associated protein I-2
UniProt Protein Name
Acidic leucine-rich nuclear phosphoprotein 32 family member B
UniProt Gene Name
ANP32B
UniProt Synonym Gene Names
APRIL; PHAPI2; PHAPI2
UniProt Entry Name
AN32B_HUMAN

Uniprot Description

ANP32B: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. Belongs to the ANP32 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 9q22.32

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function: histone binding

Biological Process: caspase activation; positive regulation of protein export from nucleus; nucleosome assembly; negative regulation of cell differentiation; vasculature development; ventricular system development; palate development; inner ear development

Research Articles on ANP32B

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Product Notes

The ANP32B anp32b (Catalog #AAA641375) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APRIL, ID (Tumor Necrosis Factor Ligand Superfamily Member 13, A Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1, TNF-related Death Ligand 1, TNFSF13, CD256, TALL2, ZTNF2, UNQ383/PRO715) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's APRIL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot and Immunohistochemistry. Dilution: Western Blot: 2-4ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml. Researchers should empirically determine the suitability of the ANP32B anp32b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APRIL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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