Rabbit APPBP2 Polyclonal Antibody | anti-APPBP2 antibody

APPBP2 Antibody

Cat. Num. AAA7122734

• Gene Names: APPBP2; PAT1; HS.84084
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: APPBP2; Polyclonal Antibody; APPBP2 Antibody; KIAA0228; PAT1; Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1; anti-APPBP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

• Applicable Applications for anti-APPBP2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; ELISA: 1:10000
• Immunogen: Synthesized peptide derived from the Internal region of human APP-BP2. at AA rangle: 390-470
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blot analysis of 293 using APP-BP2 antibody.. Secondary antibody was diluted at 1:20000)

Product Categories/Family for anti-APPBP2 antibody

Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 18104962
• NCBI GeneID: 10513
• NCBI Accession #: NP_006371.2
• NCBI GenBank Nucleotide #: NM_006380.2
• UniProt Accession #: Q92624; O95095; Q8WVC9; A8K862
• Molecular Weight: 66,853 Da
• NCBI Official Full Name: amyloid protein-binding protein 2
• NCBI Official Synonym Full Names: amyloid beta precursor protein (cytoplasmic tail) binding protein 2
• NCBI Official Symbol: APPBP2
• NCBI Official Synonym Symbols: PAT1; HS.84084
• NCBI Protein Information: amyloid protein-binding protein 2; APP-BP2; protein interacting with APP tail 1; amyloid beta precursor protein-binding protein 2
• UniProt Protein Name: Amyloid protein-binding protein 2
• Protein Family: Amyloid protein-binding protein
• UniProt Gene Name: APPBP2
• UniProt Synonym Gene Names: KIAA0228; PAT1; APP-BP2
• UniProt Entry Name: APBP2_HUMAN

NCBI Description

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

APPBP2: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 17q23.2

Cellular Component: microtubule; microtubule associated complex; cytoplasmic vesicle membrane; cytoplasm; nucleus

Molecular Function: protein binding; microtubule motor activity

Biological Process: intracellular protein transport; intracellular transport; metabolic process