Western Blot (WB)
(APPBP1 polyclonal antibody. Western Blot analysis of APPBP1 expression in rat brain.)
Mouse anti-Human, Rat APPBP1 Polyclonal Antibody
APPBP1 (NAE1, NEDD8-activating Enzyme E1 Regulatory Subunit, Amyloid beta Precursor Protein-binding Protein 1, 59kD, Amyloid Protein-binding Protein 1, Proto-oncogene Protein 1, A-116A10.1, HPP1, Ula-1)
Reactivity
Human, Rat
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
APPBP1; Polyclonal Antibody; APPBP1 (NAE1; NEDD8-activating Enzyme E1 Regulatory Subunit; Amyloid beta Precursor Protein-binding Protein 1; 59kD; Amyloid Protein-binding Protein 1; Proto-oncogene Protein 1; A-116A10.1; HPP1; Ula-1); Anti -APPBP1 (NAE1; anti-APPBP1 antibody
Host
Mouse
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human NAE1. Species Crossreactivity: rat.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL
Applicable Applications for anti-APPBP1 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human NAE1, aa1-534 (NP_003896.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(APPBP1 polyclonal antibody. Western Blot analysis of APPBP1 expression in rat brain.)
Western Blot (WB)
(APPBP1 polyclonal antibody. Western Blot analysis of APPBP1 expression in rat brain.)
Western Blot (WB)
(Western Blot analysis of NAE1 expression in transfected 293T cell line by NAE1 polyclonal antibody. Lane 1: APPBP1 transfected lysate (58.74kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of NAE1 expression in transfected 293T cell line by NAE1 polyclonal antibody. Lane 1: APPBP1 transfected lysate (58.74kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-APPBP1 antibody
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-APPBP1 antibody
Similar Products
Product Notes
The APPBP1 (Catalog #AAA643948) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The APPBP1 (NAE1, NEDD8-activating Enzyme E1 Regulatory Subunit, Amyloid beta Precursor Protein-binding Protein 1, 59kD, Amyloid Protein-binding Protein 1, Proto-oncogene Protein 1, A-116A10.1, HPP1, Ula-1) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's APPBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the APPBP1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAQLGKLLKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII DGNQVSGEDA GNNFFLQRSS IGKNRAEAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF CRFTVVVATQ LPESTSLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL EDLRLDKPFP ELREHFQSYD LDHMEKKDHS HTPWIVIIAK YLAQWYSETN GRIPKTYKEK EDFRDLIRQG ILKNENGAPE DEENFEEAIK NVNTALNTTQ IPSSIEDIFN DDRCINITKQ TPSFWILARA LKEFVAKEGQ GNLPVRGTIP DMIADSGKYI KLQNVYREKA KKDAAAVGNH VAKLLQSIGQ APESISEKEL KLLCSNSAFL RVVRCRSLAE EYGLDTINKD EIISSMDNPD NEIVLYLMLR AVDRFHKQQG RYPGVSNYQV EEDIGKLKSC LTGFLQEYGL SVMVKDDYVH EFCRYGAAEP HTIAAFLGGA AAQEVIKIIT KQFVIFNNTY IYSGMSQTSA TFQL. It is sometimes possible for the material contained within the vial of "APPBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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