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Rabbit anti-Guinea pig Apolipoprotein C2 (APOC2) Polyclonal Antibody | anti-APOC2 antibody

Cy3-Linked Polyclonal Antibody to Apolipoprotein C2 (APOC2)

Gene Names
Apoc2; apo-CII; apoC-II
Reactivity
Guinea pig
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
Apolipoprotein C2 (APOC2); Polyclonal Antibody; Cy3-Linked Polyclonal Antibody to Apolipoprotein C2 (APOC2); APC2; Apo-C2; ProapoC-II; Apolipoprotein C-II; Proapolipoprotein C-II; anti-APOC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Guinea pig
Clonality
Polyclonal
Concentration
>=100ug/ml (varies by lot)
Applicable Applications for anti-APOC2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
APOC2 (Asp32~Gln100)
Conjugation
Cy3
Cross Reactivity
Guinea pig
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032777

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,741 Da
NCBI Official Full Name
apolipoprotein C-II
NCBI Official Synonym Full Names
apolipoprotein C-II
NCBI Official Symbol
Apoc2
NCBI Official Synonym Symbols
apo-CII; apoC-II
NCBI Protein Information
apolipoprotein C-II
UniProt Protein Name
Apolipoprotein C-II
Protein Family
UniProt Gene Name
Apoc2
UniProt Synonym Gene Names
Apo-CII; ApoC-II

Uniprot Description

APOC2: Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B). It is an autosomal recessive trait characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Belongs to the apolipoprotein C2 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7 A3|7 9.94 cM

Cellular Component: chylomicron; extracellular space

Molecular Function: lipase inhibitor activity; lipid binding; phospholipase activator activity; phospholipase binding; protein homodimerization activity

Biological Process: cholesterol efflux; lipoprotein transport; negative regulation of cholesterol transport; negative regulation of lipid metabolic process; negative regulation of receptor-mediated endocytosis; phospholipid efflux; positive regulation of fatty acid biosynthetic process; positive regulation of lipoprotein lipase activity

Research Articles on APOC2

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Product Notes

The APOC2 apoc2 (Catalog #AAA2061797) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cy3-Linked Polyclonal Antibody to Apolipoprotein C2 (APOC2) reacts with Guinea pig and may cross-react with other species as described in the data sheet. AAA Biotech's Apolipoprotein C2 (APOC2) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the APOC2 apoc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Apolipoprotein C2 (APOC2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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