Rabbit anti-Human ApoF Polyclonal Antibody | anti-ApoF antibody
ApoF Antibody (Center)
Appearance: Colorless liquid
Shelf Life: 12 months
Background: Apolipoproteins are a family of fatty-acid binding proteins that transport fat through the bloodstream in the form of lipoproteins. ApoF (apolipoprotein F), also known as LTIP (lipid transfer inhibitor protein), is a 308 amino acid secreted protein that belongs to the apolipoprotein family. Expressed in liver tissues and also existing in plasma, ApoF inhibits the activity of CETP (cholesteryl ester transfer protein) and, via this inhibition, functions to regulate cholesterol transport. The gene encoding ApoF maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
NCBI and Uniprot Product Information
NCBI Description
The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol. [provided by RefSeq, Jul 2008]
Uniprot Description
APOF: Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: extracellular region
Molecular Function: lipid transporter activity; cholesterol binding; receptor binding
Biological Process: cholesterol metabolic process; triacylglycerol metabolic process; cholesterol efflux; lipid metabolic process; lipid transport
Research Articles on ApoF
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Product Notes
The ApoF apof (Catalog #AAA841121) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ApoF Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ApoF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blot: ~1:1000, IHC: ~1:10-1:50. Researchers should empirically determine the suitability of the ApoF apof for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ApoF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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