Goat APOB48R Polyclonal Antibody | anti-APOB48R antibody
Goat anti-APOB48R (mouse) Antibody
Gene Names
Apobr; Apob48r; Apob-48r
Reactivity
Expected from sequence similarity: Mouse, Rat, Dog,
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
APOB48R; Polyclonal Antibody; Goat anti-APOB48R (mouse) Antibody; Apob48r; apolipoprotein B48 receptor; Apob-48; Apob48r antibody; apolipoprotein B48 receptor antibody; Apob-48 antibody; APOB48R (mouse); anti-APOB48R antibody
Host
Goat
Reactivity
Expected from sequence similarity: Mouse, Rat, Dog,
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
QELQARLSQPKPQ
Sequence Length
942
Applicable Applications for anti-APOB48R antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave an approx.37kDa band in Mouse and Rat Spleen lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to NP_612183.1. The 37kDa band was successfully blocked by incubation with the immunizing peptide.
Western Blot: Preliminary experiments gave an approx.37kDa band in Mouse and Rat Spleen lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to NP_612183.1. The 37kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence C-QELQARLSQPKPQ, from the C Terminus of the protein sequence according to NP_612183.1.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
102,705 Da
NCBI Official Full Name
apolipoprotein B receptor
NCBI Official Synonym Full Names
apolipoprotein B receptor
NCBI Official Symbol
Apobr
NCBI Official Synonym Symbols
Apob48r; Apob-48r
NCBI Protein Information
apolipoprotein B receptor
UniProt Protein Name
Apolipoprotein B receptor
UniProt Gene Name
Apobr
UniProt Synonym Gene Names
Apob48r; Apolipoprotein B48 receptor; apoB-48R
UniProt Entry Name
APOBR_MOUSE
Uniprot Description
APOB48R: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.
Cellular Component: chylomicron; membrane; plasma membrane
Molecular Function: lipoprotein receptor activity; very-low-density lipoprotein receptor activity
Biological Process: cholesterol metabolic process; lipid metabolic process; lipid transport; steroid metabolic process; transport; triacylglycerol metabolic process
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Product Notes
The APOB48R apobr (Catalog #AAA422145) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-APOB48R (mouse) Antibody reacts with Expected from sequence similarity: Mouse, Rat, Dog, and may cross-react with other species as described in the data sheet. AAA Biotech's APOB48R can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments gave an approx.37kDa band in Mouse and Rat Spleen lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to NP_612183.1. The 37kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the APOB48R apobr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QELQARLSQP KPQ. It is sometimes possible for the material contained within the vial of "APOB48R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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