Rabbit anti-Human, Mouse APLF Polyclonal Antibody | anti-APLF antibody
APLF (Phospho-Ser116) Antibody
Gene Names
APLF; APFL; PALF; Xip1; ZCCHH1; C2orf13
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Synonyms
APLF; Polyclonal Antibody; APLF (Phospho-Ser116) Antibody; APFL; aprataxin and PNK-like factor; C2orf13; Xip1; anti-APLF antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
APLF (Phospho-Ser116) Antibody detects endogenous levels of APLF only when phosphorylated at Ser116.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
511
Applicable Applications for anti-APLF antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50~1:100
ELISA: 1:10000
ELISA: 1:10000
Target Modification
Phospho
Modification Sites
H:S116; M:S116
Immunogen
The antiserum was produced against synthesized peptide derived from human APLF around the phosphorylation site of Ser116.
Immunogen Range
82-131
Preparation and Storage
Stable at -20 degree C for at least 1 year.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56 kDa
NCBI Official Full Name
aprataxin and PNK-like factor
NCBI Official Synonym Full Names
aprataxin and PNKP like factor
NCBI Official Symbol
APLF
NCBI Official Synonym Symbols
APFL; PALF; Xip1; ZCCHH1; C2orf13
NCBI Protein Information
aprataxin and PNK-like factor
UniProt Protein Name
Aprataxin and PNK-like factor
Protein Family
UniProt Gene Name
APLF
UniProt Synonym Gene Names
C2orf13; PALF; XIP1
NCBI Description
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008]
Uniprot Description
Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Research Articles on APLF
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Product Notes
The APLF aplf (Catalog #AAA9503343) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APLF (Phospho-Ser116) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's APLF can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50~1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the APLF aplf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "APLF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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