Rabbit anti-Human, Rat APBB1IP Polyclonal Antibody | anti-APBB1IP antibody

APBB1IP Antibody

Cat. Num. AAA1493100

• Gene Names: APBB1IP; RIAM; INAG1; PREL1; RARP1
• Reactivity: Human, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: APBB1IP; Polyclonal Antibody; APBB1IP Antibody; APBB1-interacting protein 1; Proline-rich EVH1 ligand 1; PREL-1; Proline-rich protein 73; Rap1-GTP-interacting adapter molecule; RIAM; Retinoic acid-responsive proline-rich protein 1; RARP-1; PREL1; RARP1; anti-APBB1IP antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Sequence Length: 666

• Applicable Applications for anti-APBB1IP antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: WB:1:200-1000; IHC:1:20-1:200
• Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Conjugate: Non-conjugated
• Immunogen: Recombinant human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein protein (1-150aa)
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104813
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: APBB1IP antibody at 4ug/mlLane 1:HL-60 whole cell lysateLane 2:rat spleen tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 74,19 kDaObserved band size: 73 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human breast cancer using MBS1493100 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human tonsil using MBS1493100 at dilution 1:100)

Related Product Information for anti-APBB1IP antibody

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.

NCBI and Uniprot Product Information

• NCBI GI #: 56118221
• NCBI GeneID: 54518
• NCBI Accession #: NP_061916.3
• NCBI GenBank Nucleotide #: NM_019043.3
• UniProt Accession #: Q7Z5R6; Q8IWS8; Q8IYL7; Q8IZZ7
• Molecular Weight: 18,686 Da
• NCBI Official Full Name: amyloid beta A4 protein-binding family B member 1-interacting protein
• NCBI Official Synonym Full Names: amyloid beta precursor protein binding family B member 1 interacting protein
• NCBI Official Symbol: APBB1IP
• NCBI Official Synonym Symbols: RIAM; INAG1; PREL1; RARP1
• NCBI Protein Information: amyloid beta A4 precursor protein-binding family B member 1-interacting protein
• UniProt Protein Name: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
• Protein Family: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
• UniProt Gene Name: APBB1IP
• UniProt Synonym Gene Names: PREL1; RARP1; RIAM; PREL-1; RIAM; RARP-1
• UniProt Entry Name: AB1IP_HUMAN

Uniprot Description

RIAM: Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin- induced promoter activities through AP1 and SRE. Mediates Rap1- induced adhesion. Belongs to the MRL family.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 10p12.1

Cellular Component: cytoskeleton; cytosol; focal adhesion; lamellipodium; T cell receptor complex

Molecular Function: protein binding

Biological Process: blood coagulation; platelet activation; positive regulation of cell adhesion; signal transduction; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell