Immunohistochemistry (IHC)
(Anti-AP3B2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit anti-Human, Mouse AP3B2 Polyclonal Antibody | anti-AP3B2 antibody
Rabbit Polyclonal to Human AP3B2
Usage: AP3B2 antibody can be used for detection of AP3B2 by Western blot at 1-2 ug/mL.
Immunohistochemistry (IHC)
(Anti-AP3B2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-AP3B2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunofluorescence (IF)
(Immunofluorescence of AP3B2 in mouse brain tissue with AP3B2 antibody at 20 ug/ml.)
Immunofluorescence (IF)
(Immunofluorescence of AP3B2 in mouse brain tissue with AP3B2 antibody at 20 ug/ml.)
Western Blot (WB)
(Western blot analysis of AP3B2 in rat brain tissue lysate with AP3B2 antibody at (A) 1 and (B) 2 ug/ml.)
Western Blot (WB)
(Western blot analysis of AP3B2 in rat brain tissue lysate with AP3B2 antibody at (A) 1 and (B) 2 ug/ml.)
NCBI and Uniprot Product Information
NCBI Description
Adaptor protein-3 (AP3) is a heterotetrameric vesicle-coat protein complex. Some AP3 subunits are ubiquitously expressed, whereas others are expressed exclusively in neurons. The neuron-specific AP3 complex, which includes AP3B2, is thought to serve neuron-specific functions such as neurotransmitter release (Grabner et al., 2006 [PubMed 16788073]).[supplied by OMIM, Mar 2008]
Uniprot Description
AP3B2: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. Belongs to the adaptor complexes large subunit family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 15q
Cellular Component: nucleoplasm; Golgi apparatus; COPI-coated vesicle; cytoplasm; clathrin coated vesicle membrane
Molecular Function: transporter activity
Biological Process: intracellular protein transport; anterograde synaptic vesicle transport; post-Golgi vesicle-mediated transport; anterograde axon cargo transport
Research Articles on AP3B2
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Product Notes
The AP3B2 ap3b2 (Catalog #AAA248685) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human AP3B2 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AP3B2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB). IHC-P (5 ug/ml), WB (1 - 2 ug/ml) Usage: AP3B2 antibody can be used for detection of AP3B2 by Western blot at 1-2 ug/mL. Researchers should empirically determine the suitability of the AP3B2 ap3b2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AP3B2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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