Rabbit anti-Human, Mouse AOC2 Polyclonal Antibody | anti-AOC2 antibody
AOC2 Antibody
Gene Names
AOC2; RAO; DAO2; SSAO
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
AOC2; Polyclonal Antibody; AOC2 Antibody; Amine oxidase [copper containing]; Amine oxidase [copper-containing]; Amine oxidase copper containing 2 (retina specific); Amine oxidase copper containing 2; AOC2_HUMAN; DAO2; RAO; Retina specific copper amine oxidase; Retina-specific copper amine oxidase; Semicarbazide-sensitive amine oxidase; SSAO; anti-AOC2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
AOC2 Antibody detects endogenous levels of total AOC2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-AOC2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the copper/topaquinone oxidase family.
Post Translational Modifications
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
Subunit Structure
Homodimer; disulfide-linked (By similarity). Forms a heterodimer with AOC3, in vitro.
Tissue Specificity
Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis.
Function
Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-AOC2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80,516 Da
NCBI Official Full Name
retina-specific copper amine oxidase isoform b
NCBI Official Synonym Full Names
amine oxidase, copper containing 2
NCBI Official Symbol
AOC2
NCBI Official Synonym Symbols
RAO; DAO2; SSAO
NCBI Protein Information
retina-specific copper amine oxidase
UniProt Protein Name
Retina-specific copper amine oxidase
Protein Family
UniProt Gene Name
AOC2
UniProt Synonym Gene Names
RAO; SSAO
NCBI Description
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Description
Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.
Research Articles on AOC2
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Product Notes
The AOC2 aoc2 (Catalog #AAA9629389) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AOC2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AOC2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the AOC2 aoc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AOC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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