Western Blot (WB)
(AOAH Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AOAH antibody detected the AOAH protein (arrow).)
Rabbit anti-Human, mouse AOAH Polyclonal Antibody | anti-AOAH antibody
AOAH Antibody (Center)
Western Blot (WB)
(AOAH Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AOAH antibody detected the AOAH protein (arrow).)
Western Blot (WB)
(AOAH Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the AOAH antibody detected the AOAH protein (arrow).)
acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis
of acyloxylacyl-linked fatty acyl chains from bacterial
lipopolysaccharides, effectively detoxifying these molecules. The
encoded protein may play a role in modulating host inflammatory
response to gram-negative bacteria. Alternatively spliced
transcript variants have been described.
Pelak, K., et al. J. Infect. Dis. 201(8):1141-1149(2010)
Barnes, K.C., et al. J. Allergy Clin. Immunol. 118(1):70-77(2006)
Coulthard, M.G., et al. Infect. Immun. 64(5):1510-1515(1996)
Staab, J.F., et al. J. Biol. Chem. 269(38):23736-23742(1994)
NCBI and Uniprot Product Information
NCBI Description
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]
Uniprot Description
AOAH: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipase; Secreted, signal peptide; Secreted; EC 3.1.1.77
Chromosomal Location of Human Ortholog: 7p14.2
Cellular Component: extracellular region
Molecular Function: lipoprotein lipase activity; acyloxyacyl hydrolase activity; catalytic activity
Biological Process: lipid metabolic process; inflammatory response
Research Articles on AOAH
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Product Notes
The AOAH aoah (Catalog #AAA9202220) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 168-197. The AOAH Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AOAH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the AOAH aoah for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AOAH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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