Western Blot (WB)
(Western Blot analysis of Annexin VIII expression in Jurkat cell lysate.)
Rabbit anti-Human ANXA8 Polyclonal Antibody | anti-ANXA8 antibody
ANXA8 (Annexin A8, Annexin-8, Annexin VIII, Vascular Anticoagulant-beta, VAC-beta, ANX8)
Gene Names
ANXA8; ANX8
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
ANXA8; Polyclonal Antibody; ANXA8 (Annexin A8; Annexin-8; Annexin VIII; Vascular Anticoagulant-beta; VAC-beta; ANX8); Anti -ANXA8 (Annexin A8; anti-ANXA8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Annexin VIII at ~28-30kD and ~36kD.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
Applicable Applications for anti-ANXA8 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-4ug/ml
Dilution: Western Blot: 0.5-4ug/ml
Immunogen
Synthetic peptide corresponding to aa316 from human Annexin VIII.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of Annexin VIII expression in Jurkat cell lysate.)
Western Blot (WB)
(Western Blot analysis of Annexin VIII expression in Jurkat cell lysate.)
Related Product Information for anti-ANXA8 antibody
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate its role in hematopoietic cell differentiation.
Product Categories/Family for anti-ANXA8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,881 Da
NCBI Official Full Name
annexin A8 isoform 1
NCBI Official Synonym Full Names
annexin A8
NCBI Official Symbol
ANXA8
NCBI Official Synonym Symbols
ANX8
NCBI Protein Information
annexin A8; VAC-beta; annexin-8; annexin VIII; vascular anticoagulant-beta
UniProt Protein Name
Annexin A8
Protein Family
UniProt Gene Name
ANXA8
UniProt Synonym Gene Names
ANX8; VAC-beta
UniProt Entry Name
ANXA8_HUMAN
NCBI Description
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid.
Sequence similarities: Belongs to the annexin family.Contains 4 annexin repeats.
Research Articles on ANXA8
Similar Products
Product Notes
The ANXA8 anxa8 (Catalog #AAA649167) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ANXA8 (Annexin A8, Annexin-8, Annexin VIII, Vascular Anticoagulant-beta, VAC-beta, ANX8) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ANXA8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.5-4ug/ml. Researchers should empirically determine the suitability of the ANXA8 anxa8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANXA8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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