Rabbit anti-Human ANP32C Polyclonal Antibody | anti-ANP32C antibody

ANP32C, ID (ANP32C, PP32R1, Acidic leucine-rich nuclear phosphoprotein 32 family member C, Phosphoprotein 32-related protein 1, Tumorigenic protein pp32r1)

Cat. Num. AAA648308

• Gene Names: ANP32C; PP32R1
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ANP32C; Polyclonal Antibody; ID (ANP32C; PP32R1; Acidic leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1); Anti -ANP32C; anti-ANP32C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-ANP32C antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: ANP32C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the Central region of human ANP32C.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ANP32C Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ANP32C antibody detected the ANP32C protein (arrow).)

Related Product Information for anti-ANP32C antibody

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq].

Product Categories/Family for anti-ANP32C antibody

Antibodies; Abs to Leucine-rich Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 6912604
• NCBI GeneID: 23520
• NCBI Accession #: NP_036535.1
• NCBI GenBank Nucleotide #: NM_012403.1
• UniProt Accession #: O43423; Q4W5F9
• Molecular Weight: 26,762 Da
• NCBI Official Full Name: acidic leucine-rich nuclear phosphoprotein 32 family member C
• NCBI Official Synonym Full Names: acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
• NCBI Official Symbol: ANP32C
• NCBI Official Synonym Symbols: PP32R1
• NCBI Protein Information: acidic leucine-rich nuclear phosphoprotein 32 family member C; pp32 related 1; tumorigenic protein pp32r1; phosphoprotein 32-related protein 1
• UniProt Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member C
• Protein Family: Acidic leucine-rich nuclear phosphoprotein 32 family
• UniProt Gene Name: ANP32C
• UniProt Synonym Gene Names: PP32R1
• UniProt Entry Name: AN32C_HUMAN

NCBI Description

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]

Uniprot Description

Tissue specificity: Expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. Expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines. Not expressed in normal prostatic tissue. Ref.1 Ref.5

Sequence similarities: Belongs to the ANP32 family.Contains 4 LRR (leucine-rich) repeats.

Caution: The His-140 polymorphism is uncertain. It has been found in prostatic cell line without corresponding normal tissue sample. Cells transfected with this variant expressed at least twice as much proteins than native cells.