Rabbit anti-Human ANKRD49 Polyclonal Antibody | anti-ANKRD49 antibody

ANKRD49 Antibody

Cat. Num. AAA7005618

• Gene Names: ANKRD49; FGIF; GBIF
• Reactivity: Human
• Applications: ELISA
• Purity: >95%,Protein G purified
• Synonyms: ANKRD49; Polyclonal Antibody; ANKRD49 Antibody; Ankyrin repeat domain-containing protein 49; Fetal globin-inducing factor; FGIF; anti-ANKRD49 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 239

• Applicable Applications for anti-ANKRD49 antibody: ELISA (EIA)
• Immunogen: Recombinant human Ankyrin repeat domain-containing protein 49 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western BlotPositive WB detected in: HEK293 whole cell lysateAll lanes: ANKRD49 antibody at 3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 28 KDaObserved band size: 28 KDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7005618 at dilution of 1:100)

Related Product Information for anti-ANKRD49 antibody

Induces HBG1 expression (PubMed:16131492, PubMed:11162141). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway.

NCBI and Uniprot Product Information

• NCBI GI #: 41350198
• NCBI GeneID: 54851
• NCBI Accession #: NP_060174.2
• NCBI GenBank Nucleotide #: NM_017704.2
• UniProt Accession #: Q8WVL7; Q8NDF2; Q96JE5; Q9NXK7
• Molecular Weight: 27,290 Da
• NCBI Official Full Name: ankyrin repeat domain-containing protein 49
• NCBI Official Synonym Full Names: ankyrin repeat domain 49
• NCBI Official Symbol: ANKRD49
• NCBI Official Synonym Symbols: FGIF; GBIF
• NCBI Protein Information: ankyrin repeat domain-containing protein 49
• UniProt Protein Name: Ankyrin repeat domain-containing protein 49
• Protein Family: Ankyrin repeat domain-containing protein
• UniProt Gene Name: ANKRD49
• UniProt Synonym Gene Names: FGIF
• UniProt Entry Name: ANR49_HUMAN

Uniprot Description

ANKRD49: Induces HBG1 expression (PubMed:16131492, PubMed:11162141). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF- kappaB pathway. {ECO:0000250|UniProtKB:Q8VE42, ECO:0000269|PubMed:11162141, ECO:0000269|PubMed:16131492}

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: cell differentiation; positive regulation of transcription, DNA-dependent; spermatogenesis