Rabbit anti-Rat Anion Exchanger 2 Polyclonal Antibody | anti-SLC4A2 antibody
Anion Exchanger 2 (AE2)
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
SerumSerum
Synonyms
Anion Exchanger 2; Polyclonal Antibody; Anion Exchanger 2 (AE2); Anti -Anion Exchanger 2 (AE2); anti-SLC4A2 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat AE-2. Species sequence homology: mouse- 100%, rabbit-90%, human-85%, chicken-80%.
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid in PBS and 0.05% sodium azide, 40% glycerol.
Applicable Applications for anti-SLC4A2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:10,000-50,000
Dilution: Western Blot: 1:1000-1:5000
ELISA: 1:10,000-50,000
Immunogen
Synthetic peptide corresponding to a 21 AA Peptide sequence near the N-terminus of rat AE-2 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-SLC4A2 antibody
Anion exchangers (AE) are membranes proteins involved in the regulation of intracellular pH, cell volume regulation as well as in transepithelial acid/base transport. AE proteins are sodium-independent exchangers that mediates one-for-one exchange of extracellular Cl- for intracellular HCO3- ions resulting in intracellular acidification. AE proteins are encoded by a family of at least three related genes (AE1, AE2, and AE3). Numerous alternatively spliced isoforms of each AE gene are expressed in various tissues. AE proteins are exemplified by a large N-terminal cytoplasmic domain (~40-75kD) that provides binding sites for cytoskeleton protein, glycolytic enzymes and hemoglobin. The N-terminal cytoplasmic domains of AE2 are AE3 are more closely related than AE1. In fact, AE1 N-terminus is 300 aa shorter than both the AE2 and AE3. The C-terminal TM domain (~55kD) is highly conserved (~70% identity) among various AE, spans the lipid bilayer 12-14 times, and is able to mediate anion exchange by itself.
Product Categories/Family for anti-SLC4A2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
136,799 Da
NCBI Official Full Name
anion exchange protein 2 isoform 1
NCBI Official Symbol
SLC4A2
NCBI Protein Information
anion exchange protein 2; AE 2; anion exchanger 2; solute carrier family 4 member 2
UniProt Protein Name
Anion exchange protein 2
Protein Family
UniProt Gene Name
SLC4A2
UniProt Synonym Gene Names
AE2; AE 2
UniProt Entry Name
B3A2_PONAB
Uniprot Description
Function: Plasma membrane anion exchange protein of wide distribution
By similarity.
Subcellular location: Membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the anion exchanger (TC 2.A.31) family. [View classification]
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Product Notes
The SLC4A2 slc4a2 (Catalog #AAA610251) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anion Exchanger 2 (AE2) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Anion Exchanger 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000-1:5000 ELISA: 1:10,000-50,000. Researchers should empirically determine the suitability of the SLC4A2 slc4a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Anion Exchanger 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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