Western Blot (WB)
(Western Blot (WB) analysis of ANGPT4 polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:Mouse lung tissue lysateLane3:PC12 cell lysate)
Rabbit ANGPT4 Polyclonal Antibody | anti-ANGPT4 antibody
ANGPT4 Polyclonal Antibody
IHC: 1:50-1:200
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of ANGPT4 polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:Mouse lung tissue lysateLane3:PC12 cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of ANGPT4 polyclonal antibody at 1:500 dilutionLane1:HEK293T cell lysateLane2:Mouse lung tissue lysateLane3:PC12 cell lysate)
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of ANGPT4 pAb in paraffin-embedded human stomach carcinoma tissue at 1:50,showing secreted staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.)
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of ANGPT4 pAb in paraffin-embedded human stomach carcinoma tissue at 1:50,showing secreted staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.)
NCBI and Uniprot Product Information
NCBI Description
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008]
Uniprot Description
ANGPT4: Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: extracellular space; extracellular region
Molecular Function: transmembrane receptor protein tyrosine kinase activator activity; receptor tyrosine kinase binding
Biological Process: negative regulation of angiogenesis; positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; transmembrane receptor protein tyrosine kinase activation (dimerization); endothelial cell proliferation; positive regulation of blood vessel endothelial cell migration; angiogenesis; blood coagulation; negative regulation of blood vessel endothelial cell migration; leukocyte migration; negative regulation of apoptosis
Research Articles on ANGPT4
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Product Notes
The ANGPT4 angpt4 (Catalog #AAA3006649) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ANGPT4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ANGPT4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the ANGPT4 angpt4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ANGPT4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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