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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)

Rabbit anti-Human AMZ2 Polyclonal Antibody | anti-AMZ2 antibody

AMZ2 Antibody

Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
AMZ2; Polyclonal Antibody; AMZ2 Antibody; Archaemetzincin-2; archaemetzincins-2; anti-AMZ2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total AMZ2 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.7 mg/ml (varies by lot)
Sequence Length
360
Applicable Applications for anti-AMZ2 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:50-1:200
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human archaelysin family metallopeptidase 2
Target Name
AMZ2
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/40.)
Related Product Information for anti-AMZ2 antibody
AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.
Product Categories/Family for anti-AMZ2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,595 Da
NCBI Official Full Name
archaemetzincin-2 isoform 1
NCBI Official Synonym Full Names
archaelysin family metallopeptidase 2
NCBI Official Symbol
AMZ2
NCBI Protein Information
archaemetzincin-2
UniProt Protein Name
Archaemetzincin-2
Protein Family
UniProt Gene Name
AMZ2
UniProt Entry Name
AMZ2_HUMAN

Uniprot Description

AMZ2: Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2. Belongs to the peptidase M54 family.

Protein type: Protease; EC 3.-.-.-

Chromosomal Location of Human Ortholog: 17q24.2

Molecular Function: metallopeptidase activity; zinc ion binding

Biological Process: proteolysis

Research Articles on AMZ2

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Product Notes

The AMZ2 amz2 (Catalog #AAA9406775) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AMZ2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AMZ2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the AMZ2 amz2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AMZ2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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