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Testing Data

Rabbit anti-Human AMICA1 Polyclonal Antibody | anti-AMICA1 antibody

AMICA1 Antibody

Gene Names
AMICA1; JAML; AMICA; Gm638; CREA7-1; CREA7-4
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Antigen affinity purification
Synonyms
AMICA1; Polyclonal Antibody; AMICA1 Antibody; AMICA; CREA7-1; CREA7-4; FLJ37080; Gm638; JAML; MGC118814; MGC118815; anti-AMICA1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Sequence Length
305
Applicable Applications for anti-AMICA1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:5000
IHC: 1:50-1:200
IF: 1:20-1:50
Immunogen
Fusion protein of AMICA1
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

Testing Data

Testing Data

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
40,136 Da
NCBI Official Full Name
AMICA1 protein
NCBI Official Synonym Full Names
adhesion molecule, interacts with CXADR antigen 1
NCBI Official Symbol
AMICA1
NCBI Official Synonym Symbols
JAML; AMICA; Gm638; CREA7-1; CREA7-4
NCBI Protein Information
junctional adhesion molecule-like; adhesion molecule AMICA; adhesion molecule interacting with CXADR antigen 1; dendritic-cell specific protein CREA7-1; dendritic-cell specific protein CREA7-4
UniProt Protein Name
Junctional adhesion molecule-like
UniProt Gene Name
AMICA1
UniProt Synonym Gene Names
JAML
UniProt Entry Name
JAML1_HUMAN

Uniprot Description

AMICA1: an adhesion molecule that may function in the migration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells. Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells. Three alternatively spliced isoforms have been described.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: tight junction; integral to membrane; plasma membrane

Molecular Function: integrin binding; protein homodimerization activity; cell adhesion molecule binding

Biological Process: heterophilic cell adhesion; neutrophil chemotaxis; regulation of immune response; positive regulation of epithelial cell proliferation involved in wound healing; blood coagulation; gamma-delta T cell activation; leukocyte migration

Research Articles on AMICA1

Similar Products

Product Notes

The AMICA1 amica1 (Catalog #AAA2525245) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AMICA1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AMICA1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:5000 IHC: 1:50-1:200 IF: 1:20-1:50. Researchers should empirically determine the suitability of the AMICA1 amica1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AMICA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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