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SDS-PAGE (mouse testis tissue were subjected to SDS PAGE followed by western blot with AMH antibody at dilution of 1:100 )

Rabbit anti-Human, Mouse AMH Polyclonal Antibody | anti-AMH antibody

AMH Antibody

Gene Names
Amh; MIS
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purified
Synonyms
AMH; Polyclonal Antibody; AMH Antibody; anti- Mullerian hormone; MIF; MIS; anti-AMH antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purified
Sequence Length
553
Applicable Applications for anti-AMH antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1:1000
IHC: 1:10-1:100
Immunogen
Fusion protein of AMH
Calculated Molecular Weight
59kd
Observed Molecular Weight
65kd-70kd
Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34835
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles

SDS-PAGE

(mouse testis tissue were subjected to SDS PAGE followed by western blot with AMH antibody at dilution of 1:100 )

SDS-PAGE (mouse testis tissue were subjected to SDS PAGE followed by western blot with AMH antibody at dilution of 1:100 )

Immunohistochemistry

(Immunohistochemical of paraffin-embedded human ovary tumor using AMH antibody at dilution of 1:25 (under 40x lens))

Immunohistochemistry (Immunohistochemical of paraffin-embedded human ovary tumor using AMH antibody at dilution of 1:25 (under 40x lens))
Related Product Information for anti-AMH antibody
Anti-Mullerian hormone (AMH), also called Mullerian-inhibiting substance (MIS), is a hormone that is best known for its production by fetal testes in mammals and as the inhibitor of Mullerian duct development in males. AMH is also expressed in granulosa cells of pre antral and small antral follicles in the ovary. More recently, AMH has been studied for its role in ovarian folliculogenesis and as a potential marker of ovarian reserve.This antibody is specific to AMH.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
Amh protein, partial
NCBI Official Synonym Full Names
anti-Mullerian hormone
NCBI Official Symbol
Amh
NCBI Official Synonym Symbols
MIS
NCBI Protein Information
muellerian-inhibiting factor; Mullerian inhibiting substance; anti-Muellerian hormone; muellerian-inhibiting substance
UniProt Protein Name
Muellerian-inhibiting factor
UniProt Gene Name
Amh
UniProt Synonym Gene Names
AMH; MIS
UniProt Entry Name
MIS_MOUSE

NCBI Description

This gene is a member of the transforming growth factor-beta superfamily of growth and differentiation factors. The encoded protein is produced in fetal Sertoli cells during male gonadal differentiation. The protein binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in developing male embryos. In humans, some mutations in this gene are associated with persistent Mullerian duct syndrome (PMDS). [provided by RefSeq, Apr 2013]

Uniprot Description

AMH: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Defects in AMH are the cause of persistent Muellerian duct syndrome type 1 (PMDS1). PMDS1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; cytoplasm

Molecular Function: hormone activity; transforming growth factor beta receptor binding; receptor binding

Biological Process: Mullerian duct regression; cell-cell signaling; preantral ovarian follicle growth; urogenital system development; activation of NF-kappaB transcription factor

Research Articles on AMH

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Product Notes

The AMH amh (Catalog #AAA2523947) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AMH Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AMH can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:1000 IHC: 1:10-1:100. Researchers should empirically determine the suitability of the AMH amh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AMH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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