Testing Data
(Sample (30 ug of whole cell lysate)A: A431 10 % SDS PAGEPrimary antibody diluted at 1: 5000)
Rabbit anti-Human alpha 2 Glycine Receptor Polyclonal Antibody | anti-GLRA2 antibody
alpha 2 Glycine Receptor antibody
Immunohistochemistry: 1:100-1:500
Testing Data
(Sample (30 ug of whole cell lysate)A: A431 10 % SDS PAGEPrimary antibody diluted at 1: 5000)
Testing Data
(Sample (30 ug of whole cell lysate)A: A431 10 % SDS PAGEPrimary antibody diluted at 1: 5000)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded MDAMB468 xenograft, using alpha 2 Glycine Receptor antibody at 1: 500 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded MDAMB468 xenograft, using alpha 2 Glycine Receptor antibody at 1: 500 dilution.)
NCBI and Uniprot Product Information
NCBI Description
The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Uniprot Description
GLRA2: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA2 sub- subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter, ion channel; Membrane protein, multi-pass; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction
Molecular Function: transmitter-gated ion channel activity; extracellular-glycine-gated chloride channel activity; glycine binding
Biological Process: neuropeptide signaling pathway; ion transport; transmembrane transport
Research Articles on GLRA2
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Product Notes
The GLRA2 glra2 (Catalog #AAA9403961) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The alpha 2 Glycine Receptor antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's alpha 2 Glycine Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:500. Researchers should empirically determine the suitability of the GLRA2 glra2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "alpha 2 Glycine Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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