Testing Data
(Sample (30 ug of whole cell lysate) A: A549 B: HepG2 10% SDS PAGE diluted at 1:1000)
Rabbit anti-Human Alpha 1 antitrypsin Polyclonal Antibody | anti-SERPINA1 antibody
Alpha 1 antitrypsin Antibody
Gene Names
SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT
Reactivity
Human
Applications
Western Blot
Purity
Antibodies were purified by antigen-affinity chromatography.
Synonyms
Alpha 1 antitrypsin; Polyclonal Antibody; Alpha 1 antitrypsin Antibody; A1A antibody; A1AT antibody; AAT antibody; MGC23330 antibody; MGC9222 antibody; PI antibody; PI1 antibody; PRO2275 antibody; alpha1AT antibody; SERPINA1 antibody; serpin A1 antibody; alpha-1 protease inhibitor antibody; "serine (or cysteine) proteinase in; anti-SERPINA1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total Alpha 1 antitrypsin protein.
Purity/Purification
Antibodies were purified by antigen-affinity chromatography.
Form/Format
Rabbit IgG in 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration
0.81 mg/ml (varies by lot)
Sequence Length
418
Applicable Applications for anti-SERPINA1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500-1:3000
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant fragment corresponding to a region within amino acids 6 and 342 of Alpha 1 antitrypsin.
Target Name
Alpha 1 antitrypsin
Preparation and Storage
Store at -20 degree C
Testing Data
(Sample (30 ug of whole cell lysate) A: A549 B: HepG2 10% SDS PAGE diluted at 1:1000)
Testing Data
(Sample (30 ug of whole cell lysate) A: A549 B: HepG2 10% SDS PAGE diluted at 1:1000)
Related Product Information for anti-SERPINA1 antibody
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Product Categories/Family for anti-SERPINA1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,755 Da
NCBI Official Full Name
alpha-1-antitrypsin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
NCBI Official Symbol
SERPINA1
NCBI Official Synonym Symbols
PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT
NCBI Protein Information
alpha-1-antitrypsin
UniProt Protein Name
Alpha-1-antitrypsin
Protein Family
UniProt Gene Name
SERPINA1
UniProt Synonym Gene Names
AAT; PI; SPAAT
UniProt Entry Name
A1AT_HUMAN
NCBI Description
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Research Articles on SERPINA1
Similar Products
Product Notes
The SERPINA1 serpina1 (Catalog #AAA9409684) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Alpha 1 antitrypsin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Alpha 1 antitrypsin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:3000. Researchers should empirically determine the suitability of the SERPINA1 serpina1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Alpha 1 antitrypsin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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