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Western Blot (WB) (Western blot analysis of ALDH3A1 using K562 whole cell lysates)

Rabbit anti-Human, Rat ALDH3A1 Polyclonal Antibody | anti-ALDH3A1 antibody

ALDH3A1 Antibody

Gene Names
ALDH3A1; ALDH3; ALDHIII
Reactivity
Human, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ALDH3A1; Polyclonal Antibody; ALDH3A1 Antibody; Acetaldehyde dehydrogenase 3; AHD 4; AHD C; AHD4; AHDC; AL3A1_HUMAN; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase 3 family member A1; Aldehyde dehydrogenase 3A1; Aldehyde dehydrogenase; Aldehyde dehydrogenase class 3; Aldehyde dehydrogenase dimeric NADP preferring; Aldehyde dehydrogenase family 3 member A1; Aldehyde dehydrogenase family 3 subfamily A1; Aldehyde dehydrogenase family 3; subfamily A; member 1; Aldehyde dehydrogenase isozyme 3; Aldehyde dehydrogenase type III; ALDH 3; ALDH 3A1; ALDH III; ALDH; stomach type; ALDH3 A1; ALDH3; ALDH3A 1; Aldh3a1; ALDHIII; dimeric NADP-preferring; MGC10406; Stomach aldehyde dehydrogenase; Tumor associated aldehyde dehydrogenase tumor ALDH; anti-ALDH3A1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ALDH3A1 antibody detects endogenous levels of total ALDH3A1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
453
Applicable Applications for anti-ALDH3A1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
Immunogen
A synthesized peptide derived from human ALDH3A1
Subcellular Location
Cytoplasm.
Tissue Specificity
High levels in stomach, esophagus and lung; low level in the liver and kidney.
Predicted Cross Reactivity
Pig, Bovine, Horse, Dog
Similarity
Pig (100%), Bovine (100%), Horse (100%), Dog (89%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of ALDH3A1 using K562 whole cell lysates)

Western Blot (WB) (Western blot analysis of ALDH3A1 using K562 whole cell lysates)
Related Product Information for anti-ALDH3A1 antibody
Function: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity).
Subunit Structure: Homodimer.
Similarity: Belongs to the aldehyde dehydrogenase family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
218
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 50 kDa
Predicted: 51 kDa
NCBI Official Full Name
aldehyde dehydrogenase, dimeric NADP-preferring isoform 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family member A1
NCBI Official Symbol
ALDH3A1
NCBI Official Synonym Symbols
ALDH3; ALDHIII
NCBI Protein Information
aldehyde dehydrogenase, dimeric NADP-preferring
UniProt Protein Name
Aldehyde dehydrogenase, dimeric NADP-preferring
Protein Family
UniProt Gene Name
ALDH3A1
UniProt Synonym Gene Names
ALDH3

NCBI Description

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

Uniprot Description

ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (). May play a role in preventing corneal damage caused by ultraviolet light ().

Research Articles on ALDH3A1

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Product Notes

The ALDH3A1 aldh3a1 (Catalog #AAA9608821) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALDH3A1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH3A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000. Researchers should empirically determine the suitability of the ALDH3A1 aldh3a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH3A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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