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Rabbit anti-Human ALDH1A3 Polyclonal Antibody | anti-ALDH1A3 antibody

ALDH1A3, NT (Retinaldehyde Dehydrogenase 3, Aldehyde Dehydrogenase 6, Aldehyde Dehydrogenase Family 1 Member A3, ALDH6, RALDH-3, RalDH3) (FITC)

Gene Names
ALDH1A3; ALDH6; MCOP8; RALDH3; ALDH1A6
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
ALDH1A3; Polyclonal Antibody; NT (Retinaldehyde Dehydrogenase 3; Aldehyde Dehydrogenase 6; Aldehyde Dehydrogenase Family 1 Member A3; ALDH6; RALDH-3; RalDH3) (FITC); anti-ALDH1A3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ALDH1A1.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-ALDH1A3 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:10-1:50
ELISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide corresponding to a portion of amino acids located within the range aa31-60 in the N-terminal region of human ALDH1A3
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.
Product Categories/Family for anti-ALDH1A3 antibody
References
1. Moore, S., J Stud Alcohol Drugs 68(2), 192-196 (2007). 2. Collard, F., Biochimie 89(3), 369-373 (2007).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
220
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56,108 Da
NCBI Official Full Name
aldehyde dehydrogenase family 1 member A3 isoform 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family, member A3
NCBI Official Symbol
ALDH1A3
NCBI Official Synonym Symbols
ALDH6; MCOP8; RALDH3; ALDH1A6
NCBI Protein Information
aldehyde dehydrogenase family 1 member A3; acetaldehyde dehydrogenase 6; retinaldehyde dehydrogenase 3
UniProt Protein Name
Aldehyde dehydrogenase family 1 member A3
UniProt Gene Name
ALDH1A3
UniProt Synonym Gene Names
ALDH6; RALDH-3; RalDH3
UniProt Entry Name
AL1A3_HUMAN

Uniprot Description

ALDH1A3: Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system. Belongs to the aldehyde dehydrogenase family.

Protein type: Oxidoreductase; Amino Acid Metabolism - histidine; Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.2.1.5; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine

Chromosomal Location of Human Ortholog: 15q26.3

Cellular Component: cytoplasm; cytosol

Molecular Function: aldehyde dehydrogenase (NAD) activity; protein homodimerization activity; aldehyde dehydrogenase [NAD(P)+] activity; retinal dehydrogenase activity

Biological Process: inner ear morphogenesis; retinal metabolic process; righting reflex; embryonic eye morphogenesis; retinol metabolic process; positive regulation of apoptosis; olfactory pit development; retinoic acid metabolic process; optic cup morphogenesis involved in camera-type eye development; locomotory behavior; neuromuscular process controlling balance; nucleus accumbens development

Disease: Microphthalmia, Isolated 8

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Product Notes

The ALDH1A3 aldh1a3 (Catalog #AAA6462262) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ALDH1A3, NT (Retinaldehyde Dehydrogenase 3, Aldehyde Dehydrogenase 6, Aldehyde Dehydrogenase Family 1 Member A3, ALDH6, RALDH-3, RalDH3) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH1A3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:10-1:50 ELISA: 1:1,000 WB: 1:50-1:100 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ALDH1A3 aldh1a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH1A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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