Western Blot (WB)
(Western Blot analysis of AK6 in K562, Jurkat, HepG2 cell, Human fetal intestines tissue lysates in order using AK6 Rabbit pAb at dilution 1/800)
Rabbit AK6 Polyclonal Antibody | anti-AK6 antibody
AK6 Rabbit pAb
Western Blot (WB)
(Western Blot analysis of AK6 in K562, Jurkat, HepG2 cell, Human fetal intestines tissue lysates in order using AK6 Rabbit pAb at dilution 1/800)
Western Blot (WB)
(Western Blot analysis of AK6 in K562, Jurkat, HepG2 cell, Human fetal intestines tissue lysates in order using AK6 Rabbit pAb at dilution 1/800)
NCBI and Uniprot Product Information
NCBI Description
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot Description
TAFII31 iso2: a component of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is essential for mediating regulation of RNA polymerase transcription. TAFII31 binds to p53, the basal transcription factor GTF2B, and the acidic transactivator viral protein 16 (VP16). It is a coactivator for P53.
Protein type: Kinase, other; Transcription initiation complex; Acetyltransferase; DNA-binding; EC 2.7.4.3
Chromosomal Location of Human Ortholog: 5q13.2
Cellular Component: nucleoplasm; PCAF complex; transcription factor TFIID complex
Molecular Function: protein binding; histone acetyltransferase activity; DNA binding; transcription activator binding; p53 binding; protein heterodimerization activity; transcription coactivator activity
Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; viral reproduction; protein stabilization; RNA elongation from RNA polymerase II promoter; gene expression; positive regulation of transcription from RNA polymerase II promoter; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of cell growth; response to DNA damage stimulus; negative regulation of apoptosis
Research Articles on AK6
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Product Notes
The AK6 taf9 (Catalog #AAA4759355) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AK6 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AK6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000-1:5000. Researchers should empirically determine the suitability of the AK6 taf9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AK6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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