Rabbit anti-Human, Mouse AHI1 Polyclonal Antibody | anti-AHI1 antibody

AHI1 (Jouberin, Abelson Helper Integration Site 1 Protein Homolog, AHI-1, DKFZp686J1653, FLJ14023, FLJ20069) (PE)

Cat. Num. AAA6369098

• Gene Names: AHI1; ORF1; AHI-1; JBTS3; dJ71N10.1
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: AHI1; Polyclonal Antibody; AHI1 (Jouberin; Abelson Helper Integration Site 1 Protein Homolog; AHI-1; DKFZp686J1653; FLJ14023; FLJ20069) (PE); anti-AHI1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human AHI1. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Sequence Length: 3671

• Applicable Applications for anti-AHI1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human AHI1, aa1-609 (AAH94800.1).
• Immunogen Sequence: MPTAESEAKVKTKVRFEELLKTHSDLMREKKKLKKKLVRSEENISPDTIRSNLHYMKETTSDDPDTIRSNLPHIKETTSDDVSAANTNNLKKSTRVTKNKLRNTQLATENPNGDASVEEDKQGKPNKKVIKTVPQLTTQDLKPETPENKVDSTHQKTHTKPQPGVDHQKSEKANEGREETDLEEDEELMQAYQCHVTEEMAKEIKRKIRKKLKEQLTYFPSDTLFHDDKLSSEKRKKKKEVPVFSKAETSTLTISGDTVEGEQKKESSVRSVSSDSHQDDEISSMEQSTEDSMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSRDSPVYPKCLLDDDLVLGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEKENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSYRSMMALQEEKGKPVHCERHHESSSVDTEPGLEESKEVIKWKRLPGQENEDVFVLISPTMEEY
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(AHI1 rabbit polyclonal antibody. Western Blot analysis of AHI1 expression in mouse testis.)

Western Blot (WB)

(Western Blot analysis of AHI1 expression in transfected 293T cell line by AHI1 polyclonal antibody. Lane 1: AHI1 transfected lysate (70kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-AHI1 antibody

AHI1, encoding the Jouberin protein, is an alternatively spliced signaling molecule that contains seven Trp-Asp (WD) repeats, an SH3 domain, and numerous SH3-binding sites. The gene is expressed strongly in embryonic hindbrain and forebrain, and AHI1 may be required for both cerebellar and cortical development in humans. Defects in AHI1 are the cause of Joubert syndrome 3, an autosomal recessive brain congenital malformation. The exact function of the AHI1 gene is not yet known.

Product Categories/Family for anti-AHI1 antibody

Antibodies; Heat Shock Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 63101681
• NCBI GeneID: 54806
• NCBI Official Full Name: Homo sapiens Abelson helper integration site 1, mRNA
• NCBI Official Synonym Full Names: Abelson helper integration site 1
• NCBI Official Symbol: AHI1
• NCBI Official Synonym Symbols: ORF1; AHI-1; JBTS3; dJ71N10.1
• NCBI Protein Information: jouberin
• Protein Family: Jouberin

NCBI Description

This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]