Rabbit AHA1 Polyclonal Antibody | anti-AHSA1 antibody

AHA1 (Activator of Hsp90 ATPase 1)

Cat. Num. AAA619368

• Gene Names: AHSA1; p38; AHA1; C14orf3
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: AHA1; Polyclonal Antibody; AHA1 (Activator of Hsp90 ATPase 1); Anti -AHA1 (Activator of Hsp90 ATPase 1); anti-AHSA1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes endogenous level of human AHA1 protein. Species Crossreactivity: rat and mouse
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lypholized powder from PBS, pH 7.4, 0.02% sodium azide.

• Applicable Applications for anti-AHSA1 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: ELISA: 0.05-0.2ug/ml; Western Blot: 0.5-1ug/ml
• Immunogen: Synthetic peptide within residues 50-100 of human AHA1 protein (Swiss Prot: O95433). (KLH coupled)
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute by adding sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB)

(Lane 1: Mouse brain lysate Lane 2: Rat brain lysate Western blot analysis of tissue lysates using 1ug/ml MBS619368. Predicted band size 38 KD Observed band size 38 KD Additional band size 25 KD The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.)

Western Blot (WB)

(Lane 1 and 3: A549 lysate Lane 2 and 4: K562 lysate Western blot analysis of cell lysates using 1ug/ml MBS619368. Predicted band size 38 KD Observed band size 41 KD Additional band size 25 KD The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.)

Related Product Information for anti-AHSA1 antibody

AHA1 is a cochaperone that stimulates HSP90 ATPase activity. It may also affect a step in the endoplasmic reticulum with regard to Golgi trafficking. AHA1 interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein. The protein is expressed in numerous tissues, including brain, heart, skeletal muscle, and kidney tissues and, at lower levels, liver and placental tissues.

Product Categories/Family for anti-AHSA1 antibody

Antibodies; Abs to Heat Shock Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 6912280
• NCBI GeneID: 10598
• NCBI Accession #: NP_036243.1
• NCBI GenBank Nucleotide #: NM_012111.2
• UniProt Accession #: O95433; Q96IL6; Q9P060; B2R9L2
• Molecular Weight: 38,274 Da
• NCBI Official Full Name: activator of 90 kDa heat shock protein ATPase homolog 1
• NCBI Official Synonym Full Names: AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
• NCBI Official Symbol: AHSA1
• NCBI Official Synonym Symbols: p38; AHA1; C14orf3
• NCBI Protein Information: activator of 90 kDa heat shock protein ATPase homolog 1
• UniProt Protein Name: Activator of 90 kDa heat shock protein ATPase homolog 1
• Protein Family: Activator of 90 kDa heat shock protein ATPase
• UniProt Gene Name: AHSA1
• UniProt Synonym Gene Names: C14orf3; AHA1
• UniProt Entry Name: AHSA1_HUMAN

Uniprot Description

AHSA1: Cochaperone that stimulates HSP90 ATPase activity. May affect a step in the endoplasmic reticulum to Golgi trafficking. Belongs to the AHA1 family.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 14q24

Cellular Component: endoplasmic reticulum; cytoplasm; cytosol

Molecular Function: protein binding; ATPase activator activity; chaperone binding

Biological Process: positive regulation of ATPase activity; response to stress