Western Blot (WB)
(Western Blot analysis of AGFG1 in A172, Hela and 293T cells, K562 cells and human testis tissue in order using AGFG1 Rabbit pAb at dilution 1/720)
Rabbit AGFG1 Polyclonal Antibody | anti-AGFG1 antibody
AGFG1 Rabbit pAb
IHC-P: 1:50-1:200
Western Blot (WB)
(Western Blot analysis of AGFG1 in A172, Hela and 293T cells, K562 cells and human testis tissue in order using AGFG1 Rabbit pAb at dilution 1/720)
Western Blot (WB)
(Western Blot analysis of AGFG1 in A172, Hela and 293T cells, K562 cells and human testis tissue in order using AGFG1 Rabbit pAb at dilution 1/720)
Immunohistochemistry (IHC)
(Immunohistochemistry of AGFG1 in paraffin-embedded Human tonsil tissue using AGFG1 Rabbit pAb at dilution 1/60. Predicted cell location: Cytoplasm)
Immunohistochemistry (IHC)
(Immunohistochemistry of AGFG1 in paraffin-embedded Human tonsil tissue using AGFG1 Rabbit pAb at dilution 1/60. Predicted cell location: Cytoplasm)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Uniprot Description
RIP: Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. Interacts with EPS15R and EPS15. Interacts with FCHO1. Ubiquitously expressed. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Nuclear export
Chromosomal Location of Human Ortholog: 2q36.3
Cellular Component: cell projection; cell soma; cytoplasmic membrane-bound vesicle; intracellular membrane-bound organelle; nuclear pore
Molecular Function: DNA binding; GTPase activator activity; metal ion binding; protein binding; RNA binding
Biological Process: acrosome formation; intermediate filament organization; mRNA export from nucleus; multicellular organismal development; positive regulation of GTPase activity; spermatid nuclear differentiation
Research Articles on AGFG1
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Product Notes
The AGFG1 agfg1 (Catalog #AAA4759985) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AGFG1 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AGFG1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the AGFG1 agfg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AGFG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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