Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Rat Adrenomedullin (ADM) Polyclonal Antibody | anti-ADM antibody
Polyclonal Antibody to Adrenomedullin (ADM)
MGHHHHHHSGSEF-SSQF RKKWNKWALS RGKRELQASS SYPTGLVDEK TVPTQTLGLQ DKQSTSSTPQ ASTQSTAHIR VKRYRQSMNQ GSRSTGCRFG TCTMQKLAHQ IYQFTDKDKD GMAPRNKISP QGYGRRRRRS LPEVLRARTV ESSQEQTHSA PASPAHQDIS RVSR
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:RatTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:RatTissue))
NCBI and Uniprot Product Information
NCBI Description
involved in the regulation of adrenal development; plays a role in inhibition of apoptosis [RGD, Feb 2006]
Uniprot Description
ADM: AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels. Belongs to the adrenomedullin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q33
Cellular Component: cytoplasm; extracellular space
Molecular Function: adrenomedullin receptor binding; hormone activity; protein binding
Biological Process: aging; androgen metabolic process; calcium ion homeostasis; cAMP biosynthetic process; cAMP-mediated signaling; developmental growth; elevation of cytosolic calcium ion concentration; female pregnancy; G-protein coupled receptor internalization; heart development; hormone secretion; negative regulation of cell proliferation; negative regulation of vascular permeability; negative regulation of vasoconstriction; neural tube closure; neuron projection regeneration; odontogenesis of dentine-containing teeth; organ regeneration; positive regulation of angiogenesis; positive regulation of apoptosis; positive regulation of cAMP biosynthetic process; positive regulation of cAMP metabolic process; positive regulation of cell proliferation; positive regulation of heart rate; receptor internalization; regulation of systemic arterial blood pressure; regulation of the force of heart contraction; response to cold; response to glucocorticoid stimulus; response to hypoxia; response to insulin stimulus; response to lipopolysaccharide; response to organic substance; response to starvation; response to wounding; vasculogenesis
Research Articles on ADM
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Product Notes
The ADM adm (Catalog #AAA2006844) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Adrenomedullin (ADM) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Adrenomedullin (ADM) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the ADM adm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-SSQF RKKWNKWALS RGKRELQASS SYPTGLVDEK TVPTQTLGLQ DKQSTSSTPQ ASTQSTAHIR VKRYRQSMNQ GSRSTGCRFG TCTMQKLAHQ IYQFTDKDKD GMAPRNKISP QGYGRRRRRS LPEVLRARTV ESSQEQTHSA PASPAHQDIS RVSR. It is sometimes possible for the material contained within the vial of "Adrenomedullin (ADM), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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