Rabbit anti-Human, Rat ADGRB2 Polyclonal Antibody | anti-ADGRB2 antibody

ADGRB2 Antibody

Cat. Num. AAA7105197

• Gene Names: ADGRB2; BAI2
• Reactivity: Human, Rat
• Applications: ELISA, Western Blot, Immunofluorescence
• Purity: >95%, Protein G purified
• Synonyms: ADGRB2; Polyclonal Antibody; ADGRB2 Antibody; Adhesion G protein-coupled receptor B2 (Brain-specific angiogenesis inhibitor 2); BAI2; anti-ADGRB2 antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 1584

• Applicable Applications for anti-ADGRB2 antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:5000; IF: 1:50-1:200
• Immunogen: Recombinant Human Adhesion G protein-coupled receptor B2 protein (1371-1545AA)
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Species: Homo sapiens (Human)
• Research Area: Cardiovascular
• Target Names: ADGRB2
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Rat brain tissueAll lanes: ADGRB2 antibody at 3.2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 173, 172, 170 KDaObserved band size: 173 KDa)

Immunofluorescence (IF)

(Immunofluorescent analysis of HepG2 cells using MBS7105197 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-ADGRB2 antibody

Orphan receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT signaling pathway probably via a G-protein dependent pathway (PubMed:20367554). Might be involved in angiogenesis inhibition (By similarity).

Product Categories/Family for anti-ADGRB2 antibody

Neuroscience; Cardiovascular; Signal transduction

NCBI and Uniprot Product Information

• NCBI GI #: 661567369
• NCBI GeneID: 576
• NCBI Accession #: NP_001281264.1
• NCBI GenBank Nucleotide #: NM_001294335.1
• UniProt Accession #: O60241; Q5T6K0; Q8NGW8; Q96GZ9; B9EGK9
• NCBI Official Full Name: adhesion G protein-coupled receptor B2 isoform 1 preproprotein
• NCBI Official Synonym Full Names: adhesion G protein-coupled receptor B2
• NCBI Official Symbol: ADGRB2
• NCBI Official Synonym Symbols: BAI2
• NCBI Protein Information: adhesion G protein-coupled receptor B2
• UniProt Protein Name: Adhesion G protein-coupled receptor B2
• Protein Family: Adhesion G protein-coupled receptor
• UniProt Gene Name: ADGRB2

NCBI Description

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Uniprot Description

Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ (PubMed:20367554, PubMed:28891236). Involved in angiogenesis inhibition ().