Rabbit anti-Human Adenylate Kinase 1 Polyclonal Antibody | anti-ADK1 antibody

Adenylate Kinase 1 (Adenylate Kinase Isoenzyme 1, AK 1, AK1, AK-1, Adenylate Kinase Soluble, ATP-AMP Transphosphorylase, Myokinase)

Cat. Num. AAA625717

• Gene Names: ADK1; adenylate kinase 1; ADENYLATE KINASE 1; ADK1; MLE2.3; MLE2_3
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Adenylate Kinase 1; Polyclonal Antibody; Adenylate Kinase 1 (Adenylate Kinase Isoenzyme 1; AK 1; AK1; AK-1; Adenylate Kinase Soluble; ATP-AMP Transphosphorylase; Myokinase); Anti -Adenylate Kinase 1 (Adenylate Kinase Isoenzyme 1; anti-ADK1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human AK1.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.09% sodium azide.

• Applicable Applications for anti-ADK1 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: ELISA: 1:1,000; Western Blot: 1:100-1:500
• Immunogen: Synthetic peptide selected from the N-terminal region of human AK1 (KLH).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-AK1 Pab in Jurkat cell line lysate (35ug/lane). AK1(arrow) was detected using the purified Pab.)

Western Blot (WB)

(Western blot analysis of AK1 (arrow) using rabbit polyclonal AK1 Antibody (S45) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AK1 gene.)

Related Product Information for anti-ADK1 antibody

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

Product Categories/Family for anti-ADK1 antibody

Antibodies; Abs to Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 15242753
• NCBI GeneID: 836459
• NCBI Accession #: NP_201145.1
• NCBI GenBank Nucleotide #: NM_125735.3
• UniProt Accession #: O82514; Q9FMW2
• Molecular Weight: 26,932 Da
• NCBI Official Full Name: adenylate kinase 1
• NCBI Official Symbol: ADK1
• NCBI Official Synonym Symbols: adenylate kinase 1; ADENYLATE KINASE 1; ADK1; MLE2.3; MLE2_3
• NCBI Protein Information: adenylate kinase 1
• UniProt Protein Name: Adenylate kinase 1
• Protein Family: Adenosine kinase
• UniProt Gene Name: ADK1
• UniProt Entry Name: KAD1_ARATH

Uniprot Description

Function: This small ubiquitous enzyme is essential for maintenance and cell growth.

Catalytic activity: ATP + AMP = 2 ADP.

Sequence similarities: Belongs to the adenylate kinase family.