Rabbit anti-Mouse Adenylate Cyclase 6 Polyclonal Antibody | anti-ADCY6 antibody
Polyclonal Antibody to Adenylate Cyclase 6 (ADCY6)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QAFQETR GYIQARLHLQ HENRQQERLL LSVLPQHVAM EMKEDINTKK EDMMFHKIYI QKHDNVSILF ADIEGFTSLA SQCTAQELVM TLNELFARFD KLAAENHCLR IKILGDCYYC VSGLPEARAD HAHCCVEMGV
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
NCBI and Uniprot Product Information
Uniprot Description
ADCY6: a membrane-associated enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Expressed in normal thyroid and brain tissues, as well as some tumors; its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants.
Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 15|15 F1
Cellular Component: cell projection; cilium; endosome; guanylate cyclase complex, soluble; integral component of membrane; intrinsic component of plasma membrane; membrane; membrane raft; microvillus membrane; plasma membrane; sarcolemma
Molecular Function: adenylate cyclase activity; ATP binding; calcium- and calmodulin-responsive adenylate cyclase activity; guanylate cyclase activity; lyase activity; metal ion binding; nucleotide binding; phosphorus-oxygen lyase activity; protein kinase binding; receptor binding; SNARE binding
Biological Process: adenylate cyclase-activating G-protein coupled receptor signaling pathway; cAMP biosynthetic process; cellular response to catecholamine stimulus; cellular response to forskolin; cellular response to prostaglandin E stimulus; cellular response to vasopressin; cGMP biosynthetic process; cyclic nucleotide biosynthetic process; dopamine receptor signaling pathway; maintenance of protein location in plasma membrane; negative regulation of neuron projection development; regulation of blood vessel diameter; renal water homeostasis
Research Articles on ADCY6
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Product Notes
The ADCY6 adcy6 (Catalog #AAA2028409) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Adenylate Cyclase 6 (ADCY6) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Adenylate Cyclase 6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the ADCY6 adcy6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- QAFQETR GYIQARLHLQ HENRQQERLL LSVLPQHVAM EMKEDINTKK EDMMFHKIYI QKHDNVSILF ADIEGFTSLA SQCTAQELVM TLNELFARFD KLAAENHCLR IKILGDCYYC VSGLPEARAD HAHCCVEMGV. It is sometimes possible for the material contained within the vial of "Adenylate Cyclase 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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