Rabbit anti-Human, Mouse ADCY9 Polyclonal Antibody | anti-ADCY9 antibody

ADCY9, CT (ADCY9, KIAA0520, Adenylate cyclase type 9, ATP pyrophosphate-lyase 9, Adenylate cyclase type IX, Adenylyl cyclase 9) (APC)

Cat. Num. AAA6271707

• Gene Names: ADCY9; AC9
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ADCY9; Polyclonal Antibody; CT (ADCY9; KIAA0520; Adenylate cyclase type 9; ATP pyrophosphate-lyase 9; Adenylate cyclase type IX; Adenylyl cyclase 9) (APC); Adenylyl cyclase 9; anti-ADCY9 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-ADCY9 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ADCY9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1294-1323 amino acids from the C-terminal region of human ADCY9.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ADCY9 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ADCY9 antibody detected the ADCY9 protein (arrow).)

Western Blot (WB)

(ADCY9 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the ADCY9 antibody detected the ADCY9 protein (arrow).)

Related Product Information for anti-ADCY9 antibody

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.

Product Categories/Family for anti-ADCY9 antibody

Antibodies; KIAA; orf

References

Wojcik, C., et al. Am. J. Med. Genet. A 152A (2), 479-483 (2010): Olsen, J.V., et al. Cell 127(3):635-648(2006). Tantisira, K.G., et al. Hum. Mol. Genet. 14(12):1671-1677(2005). Cumbay, M.G., et al. J. Pharmacol. Exp. Ther. 310(1):108-115(2004). Small, K.M., et al. Pharmacogenetics 13(9):535-541(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 50959205
• NCBI GeneID: 115
• NCBI Accession #: NP_001107.2
• NCBI GenBank Nucleotide #: NM_001116.3
• UniProt Accession #: O60503; O60273; Q4ZHT9; Q4ZIR5; Q9BWT4; Q9UGP2; A7E2V5; D3DUD1
• Molecular Weight: 150,701 Da
• NCBI Official Full Name: adenylate cyclase type 9
• NCBI Official Synonym Full Names: adenylate cyclase 9
• NCBI Official Symbol: ADCY9
• NCBI Official Synonym Symbols: AC9
• NCBI Protein Information: adenylate cyclase type 9; adenylyl cyclase 9; ATP pyrophosphate-lyase 9; adenylate cyclase type IX; type IX ATP pyrophosphate-lyase
• UniProt Protein Name: Adenylate cyclase type 9
• Protein Family: Adenylate cyclase
• UniProt Gene Name: ADCY9
• UniProt Synonym Gene Names: KIAA0520
• UniProt Entry Name: ADCY9_HUMAN

NCBI Description

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]

Uniprot Description

ADCY9: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Transporter; Adenylyl cyclase; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Transporter, aquaporin family; EC 4.6.1.1; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: metal ion binding; ATP binding; adenylate cyclase activity

Biological Process: epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; phospholipase C activation; water transport; activation of protein kinase A; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; transmembrane transport; G-protein signaling, adenylate cyclase activating pathway