Western Blot (WB)
(Western blot analysis of anti-ADCY2 Pab in Jurkat cell line lysates (35ug/lane). ADCY2(arrow) was detected using the purified Pab.)
Rabbit anti-Human ADCY2 Polyclonal Antibody | anti-ADCY2 antibody
ADCY2, CT (Adenylate Cyclase Type 2, Adenylate Cyclase Type II, ATP Pyrophosphate-lyase 2, Adenylyl Cyclase 2, ADCY2, KIAA1060) (MaxLight 405)
Gene Names
ADCY2; AC2; HBAC2
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
ADCY2; Polyclonal Antibody; CT (Adenylate Cyclase Type 2; Adenylate Cyclase Type II; ATP Pyrophosphate-lyase 2; Adenylyl Cyclase 2; KIAA1060) (MaxLight 405); anti-ADCY2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ADCY2.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Applicable Applications for anti-ADCY2 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-1:50
FLISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:50-1:100
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the C-terminal region of human ADCY2 (KLH).
Conjugate
MaxLight405
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western blot analysis of anti-ADCY2 Pab in Jurkat cell line lysates (35ug/lane). ADCY2(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-ADCY2 Pab in Jurkat cell line lysates (35ug/lane). ADCY2(arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ADCY2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ADCY2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Product Categories/Family for anti-ADCY2 antibody
References
1. Uhl, G.R., Arch. Gen. Psychiatry 65(6), 683-693 (2008). 2. Ludwig, M.G., J. Recept. Signal Transduct. Res. 22(1-4), 79-110 (2002). 3. Cote, M., J. Clin. Endocrinol. Metab. 86(9), 4495-4503 (2001).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
103,158 Da
NCBI Official Full Name
adenylate cyclase type 2
NCBI Official Synonym Full Names
adenylate cyclase 2 (brain)
NCBI Official Symbol
ADCY2
NCBI Official Synonym Symbols
AC2; HBAC2
NCBI Protein Information
adenylate cyclase type 2; 3',5'-cyclic AMP synthetase; ATP pyrophosphate-lyase 2; adenylate cyclase II; adenylate cyclase type II; adenylyl cyclase 2; type II adenylate cyclase
UniProt Protein Name
Adenylate cyclase type 2
Protein Family
UniProt Gene Name
ADCY2
UniProt Synonym Gene Names
KIAA1060
Uniprot Description
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors ().
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Product Notes
The ADCY2 adcy2 (Catalog #AAA6461570) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADCY2, CT (Adenylate Cyclase Type 2, Adenylate Cyclase Type II, ATP Pyrophosphate-lyase 2, Adenylyl Cyclase 2, ADCY2, KIAA1060) (MaxLight 405) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADCY2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-1:50 FLISA: 1:1,000 WB: 1:50-1:100 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ADCY2 adcy2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADCY2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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