Goat ADAP1 Polyclonal Antibody | anti-ADAP1 antibody

ADAP1 (Arf-GAP with Dual PH Domain-containing Protein 1, Centaurin-alpha-1, Cnt-a1, Putative MAPK-activating Protein PM25, CENTA1)

Cat. Num. AAA6013449

• Gene Names: ADAP1; GCS1L; CENTA1; p42IP4
• Reactivity: Canine, Human, Mouse, Porcine, Rat
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: ADAP1; Polyclonal Antibody; ADAP1 (Arf-GAP with Dual PH Domain-containing Protein 1; Centaurin-alpha-1; Cnt-a1; Putative MAPK-activating Protein PM25; CENTA1); Anti -ADAP1 (Arf-GAP with Dual PH Domain-containing Protein 1; anti-ADAP1 antibody

• Host: Goat
• Reactivity: Canine, Human, Mouse, Porcine, Rat
• Clonality: Polyclonal
• Specificity: Recognizes human ADAP1. Species Crossreactivity
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

• Applicable Applications for anti-ADAP1 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: ELISA: 1:32,000; Western Blot: 1-3ug/ml, observed in human and mouse brain lysates on ~40kD bands
• Immunogen: Synthetic peptide corresponding to C-QEYAVEAHFKHKP, from ADAP1, at C-terminal (NP_006860.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chemiluminescence

((1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Related Product Information for anti-ADAP1 antibody

GTPase-activating protein for the ADP ribosylation factor family. Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).

Product Categories/Family for anti-ADAP1 antibody

Antibodies; Abs to Nuclear Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 546232203
• NCBI GeneID: 11033
• NCBI Accession #: NP_001271237.1
• NCBI GenBank Nucleotide #: NM_001284308.1
• UniProt Accession #: O75689; A4D2Q2
• Molecular Weight: 43,395 Da
• NCBI Official Full Name: arf-GAP with dual PH domain-containing protein 1 isoform 2
• NCBI Official Synonym Full Names: ArfGAP with dual PH domains 1
• NCBI Official Symbol: ADAP1
• NCBI Official Synonym Symbols: GCS1L; CENTA1; p42IP4
• NCBI Protein Information: arf-GAP with dual PH domain-containing protein 1; cnt-a1; centaurin-alpha; centaurin-alpha-1; centaurin, alpha 1; putative MAPK-activating protein PM25
• UniProt Protein Name: Arf-GAP with dual PH domain-containing protein 1
• Protein Family: Arf-GAP with dual PH domain-containing protein
• UniProt Gene Name: ADAP1
• UniProt Synonym Gene Names: CENTA1; Cnt-a1
• UniProt Entry Name: ADAP1_HUMAN

Uniprot Description

CENTA1: GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).

Protein type: GAPs, ARF; GAPs

Chromosomal Location of Human Ortholog: 7p22.3

Cellular Component: cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; phosphatidylinositol-3,4,5-triphosphate binding; zinc ion binding; inositol 1,3,4,5 tetrakisphosphate binding

Biological Process: regulation of GTPase activity; cell surface receptor linked signal transduction; positive regulation of GTPase activity