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Testing Data

Rabbit anti-Human ADAMTS1 Polyclonal Antibody | anti-ADAMTS1 antibody

ADAMTS1 Antibody

Gene Names
ADAMTS1; C3-C5; METH1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Synonyms
ADAMTS1; Polyclonal Antibody; ADAMTS1 Antibody; anti-ADAMTS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 2% BSA and 0.02% NaN3
Sequence Length
967
Applicable Applications for anti-ADAMTS1 antibody
Peptide ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA: 1:1,000-1:10,000
IHC: 1:100-500
Reconstitution
Reconstitute in 200ul sterile H2O.
Preparation and Storage
The Lyophilized antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data
Related Product Information for anti-ADAMTS1 antibody
Rabbit polyclonal ADAMTS1 (1) antibody was raised against a 13 amino acid peptide corresponding to the C terminus residues of human ADAMTS1.
References
(1) Ng, Y.H., Zhu, H., Pallen, C.J., et al. Differential effects of interleukin-1beta and transforming growth factor-beta1 on the expression of the inflammation-associated protein, ADAMTS-1, in human decidual stromal cells in vitro. Hum. Reprod.2006; 21 (8):1990-1999.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
105,358 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 1 preproprotein
NCBI Official Synonym Full Names
ADAM metallopeptidase with thrombospondin type 1 motif 1
NCBI Official Symbol
ADAMTS1
NCBI Official Synonym Symbols
C3-C5; METH1
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 1
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 1
UniProt Gene Name
ADAMTS1
UniProt Synonym Gene Names
KIAA1346; METH1; ADAM-TS 1; ADAM-TS1; ADAMTS-1

NCBI Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008]

Uniprot Description

Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.

Research Articles on ADAMTS1

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Product Notes

The ADAMTS1 adamts1 (Catalog #AAA856495) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADAMTS1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ADAMTS1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Immunohistochemistry (IHC). Peptide ELISA: 1:1,000-1:10,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the ADAMTS1 adamts1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADAMTS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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