Western Blot (WB)
(ACTR3B polyclonal antibody. Western Blot analysis of ACTR3B expression in human kidney.)
Mouse anti-Human ACTR3B Polyclonal Antibody | anti-ACTR3B antibody
ACTR3B (Actin-related Protein 3B, Actin-like Protein 3B, ARP3-beta, Actin-related Protein ARP4, ARP4, ARP11, DKFZp686O24114)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(ACTR3B polyclonal antibody. Western Blot analysis of ACTR3B expression in human kidney.)
Western Blot (WB)
(ACTR3B polyclonal antibody. Western Blot analysis of ACTR3B expression in human kidney.)
Western Blot (WB)
(Western Blot analysis of ACTR3B expression in transfected 293T cell line by ACTR3B polyclonal antibody. Lane 1: ACTR3B transfected lysate (45.98kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of ACTR3B expression in transfected 293T cell line by ACTR3B polyclonal antibody. Lane 1: ACTR3B transfected lysate (45.98kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Uniprot Description
Function: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. Ref.7
Subunit structure: Interacts with the Arp2/3 complex composed of ARP2, ARP3, ARPC1B, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.
Subcellular location: Cytoplasm › cytoskeleton
By similarity. Cell projection
By similarity.
Tissue specificity: Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential. Ref.1 Ref.6
Sequence similarities: Belongs to the actin family. ARP3 subfamily.
Sequence caution: The sequence AAP97150.1 differs from that shown. Reason: Frameshift at several positions.
Research Articles on ACTR3B
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Product Notes
The ACTR3B actr3b (Catalog #AAA648126) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ACTR3B (Actin-related Protein 3B, Actin-like Protein 3B, ARP3-beta, Actin-related Protein ARP4, ARP4, ARP11, DKFZp686O24114) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACTR3B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the ACTR3B actr3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAGSLPPCVV DCGTGYTKLG YAGNTEPQFI IPSCIAIRES AKVVDQAQRR VLRGVDDLDF FIGDEAIDKP TYATKWPIRH GIIEDWDLME RFMEQVVFKY LRAEPEDHYF LMTEPPLNTP ENREYLAEIM FESFNVPGLY IAVQAVLALA ASWTSRQVGE RTLTGIVIDS GDGVTHVIPV AEGYVIGSCI KHIPIAGRDI TYFIQQLLRE REVGIPPEQS LETAKAIKEK YCYICPDIVK EFAKYDVDPR KWIKQYTGIN AINQKKFVID VGYERFLGPE IFFHPEFANP DFMESISDVV DEVIQNCPID VRRPLYKNVV LSGGSTMFRD FGRRLQRDLK RVVDARLRLS EELSGGRIKP KPVEVQVVTH HMQRYAVWFG GSMLASTPEF FQVCHTKKDY EEYGPSICRH NPVFGVMS. It is sometimes possible for the material contained within the vial of "ACTR3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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