Testing Data
(All lanes : Anti-ACTR2 Antibody (C-term) at 1:1000 dilutionnLane 1: Hela whole cell lysatenLane 2: MCF-7 whole cell lysatennLysates/proteins at 20 u03bcg per lane. nnSecondarynGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. nnPredicted band size : 45 kDannBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human ACTR2 Polyclonal Antibody | anti-ACTR2 antibody
ACTR2 (C-term) Rabbit pAb
IHC: 1:50~100
FC/FACS: 1:10~50
Testing Data
(All lanes : Anti-ACTR2 Antibody (C-term) at 1:1000 dilutionnLane 1: Hela whole cell lysatenLane 2: MCF-7 whole cell lysatennLysates/proteins at 20 u03bcg per lane. nnSecondarynGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. nnPredicted band size : 45 kDannBlocking/Dilution buffer: 5% NFDM/TBST.)
Testing Data
(All lanes : Anti-ACTR2 Antibody (C-term) at 1:1000 dilutionnLane 1: Hela whole cell lysatenLane 2: MCF-7 whole cell lysatennLysates/proteins at 20 u03bcg per lane. nnSecondarynGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. nnPredicted band size : 45 kDannBlocking/Dilution buffer: 5% NFDM/TBST.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ACTR2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry;)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ACTR2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry;)
Flow Cytometry (FC/FACS)
(ACTR2 Antibody (C-term) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(ACTR2 Antibody (C-term) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
ARP2: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Belongs to the actin family. ARP2 subfamily.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal; Actin-binding
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: Arp2/3 protein complex; cell projection; focal adhesion; membrane; cytoplasm; cytosol; actin cap; actin cytoskeleton
Molecular Function: actin filament binding; structural constituent of cytoskeleton; ATP binding
Biological Process: meiotic chromosome movement towards spindle pole; axon guidance; asymmetric cell division; ephrin receptor signaling pathway; establishment and/or maintenance of cell polarity; innate immune response; cilium biogenesis; cytokinesis after meiosis; cell motility; cytoplasmic transport; spindle localization
Research Articles on ACTR2
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Product Notes
The ACTR2 actr2 (Catalog #AAA4753704) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACTR2 (C-term) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACTR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Flow Cytometry (FC/FACS). WB: 1:1000 IHC: 1:50~100 FC/FACS: 1:10~50. Researchers should empirically determine the suitability of the ACTR2 actr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACTR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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