Western Blot (WB)
(Western blot analysis of HepG2 HL60 and K562 cell lysates using ACTL6B Polyclonal Antibody at dilution of 1:800)
Rabbit ACTL6B Polyclonal Antibody | anti-ACTL6B antibody
ACTL6B Polyclonal Antibody
IHC: 1:50-1:300
ELISA: 1:5000-1:10000
Western Blot (WB)
(Western blot analysis of HepG2 HL60 and K562 cell lysates using ACTL6B Polyclonal Antibody at dilution of 1:800)
Western Blot (WB)
(Western blot analysis of HepG2 HL60 and K562 cell lysates using ACTL6B Polyclonal Antibody at dilution of 1:800)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:55(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ACTL6B Polyclonal Antibody at dilution of 1:55(×200))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Uniprot Description
BAF53B: a protein of the actin family involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for maximal ATPase activity of the helicase SMARCA4 and for association of the SMARCA4 containing remodelling complex BAF with chromatin/nuclear matrix.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 7q22
Cellular Component: nucleolus; nucleus; SWI/SNF complex
Molecular Function: structural constituent of cytoskeleton; transcription coactivator activity
Biological Process: chromatin remodeling; establishment and/or maintenance of chromatin architecture; regulation of transcription from RNA polymerase II promoter; spinal cord development; transcription, DNA-dependent
Research Articles on ACTL6B
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Product Notes
The ACTL6B actl6b (Catalog #AAA2562849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ACTL6B Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ACTL6B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:5000 IHC: 1:50-1:300 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the ACTL6B actl6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACTL6B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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