Rabbit ACAT2 Polyclonal Antibody | anti-ACAT2 antibody

ACAT2 Polyclonal Antibody

Cat. Num. AAA3008924

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: ACAT2; Polyclonal Antibody; ACAT2 Polyclonal Antibody; ACTL; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase; anti-ACAT2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: ACAT2 polyclonal antibody detects endogenous levels of ACAT2 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 397

• Applicable Applications for anti-ACAT2 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant protein of human ACAT2.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using ACAT2 antibody.)

Related Product Information for anti-ACAT2 antibody

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 52000838
• NCBI GeneID: 39
• UniProt Accession #: Q9BWD1
• Molecular Weight: ~ 41kDa
• NCBI Official Full Name: Acetyl-CoA acetyltransferase, cytosolic
• NCBI Official Synonym Full Names: acetyl-CoA acetyltransferase 2
• NCBI Official Symbol: ACAT2
• NCBI Protein Information: acetyl-CoA acetyltransferase, cytosolic
• UniProt Protein Name: Acetyl-CoA acetyltransferase, cytosolic
• Protein Family: Acetyl-CoA acetyltransferase
• UniProt Gene Name: ACAT2
• UniProt Synonym Gene Names: ACTL
• UniProt Entry Name: THIC_HUMAN

NCBI Description

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Uniprot Description

ACAT2: The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008]

Protein type: Carbohydrate Metabolism - butanoate; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - pyruvate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - tryptophan; Acetyltransferase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Carbohydrate Metabolism - propanoate; EC 2.3.1.9; Lipid Metabolism - fatty acid; Amino Acid Metabolism - lysine degradation

Chromosomal Location of Human Ortholog: 6q25.3

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: acetyl-CoA C-acetyltransferase activity

Biological Process: lipid metabolic process

Disease: Acetyl-coa Acetyltransferase-2 Deficiency